Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Effect of Mixture of Fermented Artemisiae Argi Folium and Fermented Sophorae Radix on Hydrogen Peroxide Production within Mouse Macrophage Raw 264.7 with EtOH and Nicotine

고삼과 애엽의 발효 혼합물이 에탄올과 니코틴으로 유발된 마우스 대식세포 내 hydrogen peroxide 생성감소에 미치는 영향

  • Park, Wan-Su (College of Oriental Medicine, Kyungwon University) ;
  • Kim, Do-Hoon (College of Oriental Medicine, Kyungwon University)
  • 박완수 (경원대학교 한의과대학 한의학과) ;
  • 김도훈 (경원대학교 한의과대학 한의학과)
  • Published : 2008.10.25
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Abstract

The purpose of this study is to investigate the effect of a mixture of fermented Artemisiae Argi Folium and fermented Sophorae Radix (FAS) on hydrogen peroxide production within mouse macrophage Raw 264.7 with ethanol (EtOH) and nicotine. Artemisiae Argi Folium is known to have the antibacterial, immune-enhancing properties. And Sophorae Radix is also known to have the antibacterial, anti-inflammatory, anti-allergic properties. EtOH and nicotine are the ones of toxicants which could impair immunocytes like macrophage. EtOH and nicotine reduce the intracellular production of hydrogen peroxide ($H_2O_2$) of Raw 264.7. FAS increased the production of hydrogen peroxide reduced by EtOH and nicotine within Raw 264.7. These results indicate that FAS could restore the immuno-activity of macrophage impaired by EtOH and nicotine.

Keywords

References

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