THE DEVELOPMENT OF INDWELLING WIRELESS PH TELEMETRY OF INTRAORAL ACIDITY

구강 내 산도의 생체 내 측정을 위한 wireless pH telemetry의 개발

  • Kim, Hyung-Jun (Department of Pediatric Dentistry, School of Dentistry, Pusan National University) ;
  • Kim, Jae-Moon (Department of Pediatric Dentistry, School of Dentistry, Pusan National University) ;
  • Jeong, Tae-Sung (Department of Pediatric Dentistry, School of Dentistry, Pusan National University) ;
  • Kim, Shin (Department of Pediatric Dentistry, School of Dentistry, Pusan National University)
  • 김형준 (부산대학교 치과대학 소아치과학교실) ;
  • 김재문 (부산대학교 치과대학 소아치과학교실) ;
  • 정태성 (부산대학교 치과대학 소아치과학교실) ;
  • 김신 (부산대학교 치과대학 소아치과학교실)
  • Published : 2008.02.29

Abstract

The purpose of this study was to develop the wireless pH telemetry lasting longer than 24 hours in the mouth to overcome the limits of conventional wire telemetry previously used for salivary and plaque pH measurement, and to assess its effectiveness. We developed a wireless pH telemeter which can measure and store the pH profile data during more than 24 hours. It was composed of intraoral part; pH sensor of antimony electrode, battery and microprocessor for data storage, and extraoral part; control/data receiver and data analyzing software which was newly made for this device. After inspecting wireless electrode for accurate measurement, it was attached to the removable intraoral appliance and delivered to the volunteer who was told to wear except brushing time, retrieved after 24 hours and finally the pH profile data was extracted and analyzed. When compared with conventional wire telemetry, this device showed similar results and induced less discomfort to examinees. The data showed pH changes at same time when examinees ate various scheduled foods and beverages. With this method it became possible to accurately measure pH changes within mouth for long time in accordance with individual's lifestyle, definitely reducing the discomfort inflicted to the examinees' life.

치아 우식증과 침식증의 진단과 예방에 있어 구강 내 환경, 특히 산도를 정밀하게 평가하는 것은 매우 중요한 일이다. 본 연구는 구강 내의 산도측정을 위한 기존 방법들의 단점을 보완하고자 구강 내 무선 pH 원격측정 방법을 개발하고, 실제로 측정시의 효율성을 얻기 위해 시행되었다. 구강 외로 부착되는 부가적인 장치 없이 구강 내에만 장착하여 24시간 이상 수소이온농도지수(이하 pH)를 측정할 수 있는 무선 원격측정장치를 개발하고, 정확한 산도의 측정이 가능한지를 검증하였다. 그리고 이 장치를 실제 구강 내에 장착하여 피검자로 하여금 24시간 동안의 시간별 상세한 섭식과 활동 내용, 수면 상태를 기록하도록 하고 24시간 후 구강으로부터 수거하여 지난 24시간 동안의 pH의 변화를 획득하고 분석하였다. 그 결과, 구강 내 장치와 구강 외 장치로 이루어진 구강 내 무선 pH 원격측정방법의 개발에 성공하였으며 24시간 동안 피검자의 구강 내 pH 변화를 측정한 결과, 피검자가 실제 섭취하였던 시간과 음식 종류에 일치하게 측정치를 얻을 수 있었다. 본 연구를 통하여 장시간 무선 pH 원격측정방법을 이용하여 구강 내 pH를 측정할 수 있게 됨으로써, 기존의 유선 pH 원격측정방법이 가진 한계점을 극복할 수 있게 되어 구강 내 환경이나 우식학과 관련된 보다 광범위한 연구가 가능하게 될 것이다.

Keywords

References

  1. Axelsson P : Diagnosis and risk prediction of dental caries. Quintessence publishing, Illinois, p.57-69, 2000.
  2. Riva TD, Cor VL : Sugars and dental caries. Am J Clin Nutr, 78:881S-92S, 2003.
  3. 대한소아치과학회 : 소아.청소년 치과학. 신흥인터내셔날, 서울, p.155-157, 2007.
  4. Norman T : Association of Diet with Dental Caries in Preschool Children. Dent Clin N Am, 49:725-737, 2005. https://doi.org/10.1016/j.cden.2005.05.011
  5. Jensen ME : Diet and denal caries. Dent Clin N Am, 43:615-633, 1999.
  6. 이경호, 정태성, 김신 : 탄산음료의 법랑질 침식효과에 대한 연구. 대한소아치과학회지, 32:144-151, 2005.
  7. Jarvinen VK, Rytomaa II, Heinonen OP : Risk factors in dental erosion. J Dent Res, 70:942-947, 1991. https://doi.org/10.1177/00220345910700060601
  8. Rytomaa I, Meurman JH, Koskinen J, et al. : In vitro erosion of bovine enamel caused by acidic drinks and other foodstuffs. Scand J Dent Re, 96:324-333, 1988.
  9. Johansson AK, Lingstrom P, Imfeld T, et al. : Influence of drinking method on tooth-surface pH in relation to dental erosion. Eur J Oral Sci, 112:484-489, 2004. https://doi.org/10.1111/j.1600-0722.2004.00172.x
  10. Simpson A, Shaw L, Smith AJ : Tooth surface pH during drinking of black tea. Br Dent J, 190:374- 376, 2001.
  11. Bartlett DW, Bureau GP, Anggiansah A : Evaluation of the pH of a New Carbonated Soft Drink Beverage: An in vivo investigation. J Prosthodont, 12:21-25, 2003. https://doi.org/10.1053/jopr.2003.3
  12. Moazzez R, Smith BG, Bartlett DW : Oral pH and drinking habit during ingestion of a carbonated drink in a group of adolescents with dental erosion. J Dent, 28:395-397, 2000. https://doi.org/10.1016/S0300-5712(00)00020-8
  13. Rees JS : The role of drinks in tooth surface loss. Dental Update, 31:318-326, 2004.
  14. Johansson AK, Lingstrom P, Birkhed D : Comparison of factors potentially related to the occurrence of dental erosion in high- and low-erosion groups. Eur J Oral Sci, 110:204-211, 2002. https://doi.org/10.1034/j.1600-0447.2002.11211.x
  15. Stephan RM : Intra-oral hydrogen-ion concentrations associated with dental caries activity. J Dent Res, 23:257-266, 1944. https://doi.org/10.1177/00220345440230040401
  16. Kleinberg I, Jenkins GN : Studies in the pH of plaque in interpoximal area after eating sweets and starchy foods. J Dent Res, 35:964, 1956.
  17. Curzon ME, Hefferren JJ : Modern methods for assessing the cariogenic and erosive potential of foods. Br Dent J, 191:41-46, 2001.
  18. Stephan RM : Changes in hydrogen ion concentraion on tooth surfaces and in carious lesions. J Am Dent Assoc, 27:718, 1940.
  19. Fosdick LS, Campaigne EE, Fancher O : Rate of acid formation in carious areas: the etiology of dental caries. Ill Dent J, 10:85-95, 1941.
  20. Frostell G : A method for evaluation of acid potentialities of foods. Acta Odontol Scand, 28:599-608, 1970. https://doi.org/10.3109/00016357009058585
  21. Edgar WM, Bibby BG, Mundorff S, et al. : Acid production in plaques after eating snacks: modifying factors in foods. J Am Dent Assoc, 90:418-425, 1975.
  22. Kleinberg I, Jenkins GN, Chatterjee R, et al. : The antimony pH electrode and its role in the assessment and interpretation of dental plaque pH. J Dent Res, 61:1139-1147, 1982. https://doi.org/10.1177/00220345820610100601
  23. Scheie AA, Fejerskov O, Lingstr¨om P, et al. : Use of palladium touch microelectrodes under field conditions for in vivo assessment of dental plaque pH in children. Caries res, 26:44-52, 1992. https://doi.org/10.1159/000261426
  24. Graf H, M?hlemann HR : Telemetry of plaque pH from interdental areas. Helv Odontol Acta, 10:94- 101, 1966.
  25. Pandolfino JE, Ghosh S, Zhang Q, et al. : Slimline vs. glass pH electrodes: what degree of accuracy should we expect? Aliment Pharmacol Ther, 23:331- 340, 2006. https://doi.org/10.1111/j.1365-2036.2006.02750.x
  26. 강종미, 이정석, 이종갑 : 미취학 아동의 우식유발성 평가 및 치아우식경험과 식이와의 상관관계에 관한 연구. 대한소아치과학회지, 10:47-55, 1983.
  27. Anderson P, Hector MP, Rampersad MA: Critical pH in resting and stimulated whole saliva in groups of children and adults. Int J Paediatr Dent, 11:266- 273, 2001.
  28. 정우진, 이상훈, 한세현 : 유아용 조제 분유가 치태 pH에 미치는 영향에 관한 연구. 대한소아치과학회지, 25:93- 102, 1998.
  29. 안호영, 이광희, 김대업 : 산성 음료에 의한 법랑질의 침식과 인공타액에 의한 재광화. 대한소아치과학회지, 29:84- 91, 2002.
  30. Dugmore CR, Rock WP : A multifactorial analysis of factors associated with dental erosion. Br Dent J, 196:283-286, 2004. https://doi.org/10.1038/sj.bdj.4811041
  31. 서동구 : Telemetry를 이용한 기호성 음료의 구강내 pH 변화 및 회복속도측정. 연세대학교 대학원 석사학위논문, 2005.
  32. Schachtele CF, Jensen ME : Comparison of methods for monitoring changes in the pH of human dental plaque. J Dent Res, 61:1117-1125, 1982. https://doi.org/10.1177/00220345820610100201
  33. Lingstrom P, Imfeld T, Birkhed D : Comparison of three different methods for measurement of plaquepH in humans after consumption of soft bread and potato chips. J Dent Res, 72:865-870, 1993. https://doi.org/10.1177/00220345930720050601
  34. Park KK, Schemehorn BR, Stookey GK, et al. : Acidogenicity of high-intensity sweeteners and polyols. Am J Dent, 8:23-26, 1995.
  35. Hochman JA, Favaloro-Sabatier J : Tolerance and reliability of wireless pH monitoring in children. J Pediatr Gastroenterol Nutr, 41:411-415, 2005. https://doi.org/10.1097/01.mpg.0000177312.81071.c8
  36. Wang WX, Yan GZ, Sun F, et al. : A non-invasive method for gastrointestinal parameter monitoring. World J Gastroenterol, 11:521-524, 2005.
  37. Rosenfeldt FL, Ou R, Smith JA, et al. : Evaluation of a miniature antimony electrode for measurement of myocardial pH. J Med Eng Technol, 23:119-126, 1999. https://doi.org/10.1080/030919099294168
  38. Jensen ME : Telemetric Methods using ion-specific electrodes. Adv Dent Res, 1:92-98, 1987.