대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제29권2호
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- Pages.490-499
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- 2008
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- 1226-9174(pISSN)
천화분 추출물이 혈관신생 및 암세포성장에 미치는 영향
Effects of Trichosanthes kirilowii Extract against Angiogenesis and Various Tumor Cells' Growth
- 김동우 (대전대학교 동서암센터) ;
- 이종훈 (대전대학교 동서암센터) ;
-
유화승
(대전대학교 동서암센터) ;
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조정효
(대전대학교 동서암센터) ;
-
이연월
(대전대학교 동서암센터) ;
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손창규
(대전대학교 동서암센터) ;
-
조종관
(대전대학교 동서암센터)
- Kim, Dong-Woo (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
- Lee, Jong-Hoon (Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
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Yoo, Hwa-Seung
(Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
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Cho, Jung-Hyo
(Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
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Lee, Yeon-Weol
(Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
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Son, Chang-Gue
(Department of East-West Cancer Center, Oriental Hospital of Daejeon University) ;
-
Cho, Chong-Kwan
(Department of East-West Cancer Center, Oriental Hospital of Daejeon University)
- 발행 : 2008.06.30
초록
Objectives : This study was aimed to elucidate the effects of Trichosanthes kirilowii extract (TKE) on the angiogenesis and growth of tumor cells. Methods : Tube formation assay was performed by using human umbilical vein endothelial cells (HUVEC), and anchorage dependent colony assay was performed by using B16-F10 melanoma, Hep G2 and HT1080, CT-26 and SNU-1 cells. Results : For HUVEC, TKE at a level of more than 100