Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Soraphinol C, a New Free-Radical Scavenger from Sorangium cellulosum

  • Li, Xuemei (College of Pharmacy, Sungkyunkwan University) ;
  • Yu, Tae-Kyung (Division of Marine Environment and Bioscience, Korea Maritime University) ;
  • Kwak, Jong-Hwan (College of Pharmacy, Sungkyunkwan University) ;
  • Son, Byoung-Yil (Research Institute ofMarine Science and Technology, Korea Maritime University) ;
  • Seo, Young-Wan (Division of Marine Environment and Bioscience, Korea Maritime University) ;
  • Zee, Ok-Pyo (College of Pharmacy, Sungkyunkwan University) ;
  • Ahn, Jong-Woong (Division of Marine Environment and Bioscience, Korea Maritime University)
  • Published : 2008.03.31
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Abstract

A new compound named soraphinol C (1) was isolated from myxobacteria Sorangium cellulosum KM1001 a soil isolate, together with a structurally related known compound, 4-hydroxysattabacin (2). These compounds were isolated by silica gel column chromatography and recycling preparative HPLC, consecutively. The structures of the compounds were determined on the basis of combined spectroscopic analyses. Compounds 1 and 2 exhibited antioxidant activity as a radical scavenger in the experiment using a hydrophilic free-radical initiator, 2,2'-azobis(2-amidinopropane)dihydrochloride with ORAC values of 0.956 and 0.617, respectively.

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References

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