대한기계학회논문집B (Transactions of the Korean Society of Mechanical Engineers B)

  • 제32권11호
  • /
  • Pages.891-896
  • /
  • 2008
  • /
  • 1226-4881(pISSN)
  • /
  • 2288-5324(eISSN)
대한기계학회 (The Korean Society of Mechanical Engineers)
권호 표지
DOI QR코드

DOI QR Code

협착 동맥에서의 맥동 혈류 유동에 대한 수치해석적 연구

Numerical Study of Pulsatile Blood Flow in Stenotic Artery

  • 서태원 (국립안동대학교 기계공학부) ;
  • 발행 : 2008.11.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

In the present computational study, simple stenotic artery models using pulsatile flow condition were investigated. A 1 Hz non-reversing sinusoidal velocity for pulsatile flow was imposed at the flow inlet and the corresponding Womersley number based on the vessel radius is 2.75. The simple stenotic geometries have been used that consist of 25%, 50% and 75% semicircular constriction in a cylindrical tube. In this paper, numerical solutions are presented for a first harmonic oscillatory flow using commercial software ADINA 8.4. As stenosis and Reynolds number increase, the maximum wall shear stress(WSS) increases while the minimum WSS decreases. As the stenotic rate increases, the pressure drop at the throat severely decreases to collapse the artery and plaque. It is found that the fluid mechanical disturbances due to the constriction were highly sensitive with rate of stenosis and Reynolds number. When Reynolds number and stenosis increase, the larger recirculation region exists. In this recirculation region the possibility of plaque attachment is increasingly higher. The present results enhance our understanding of the hemodynamics of a stenotic artery.

키워드

참고문헌

  1. Nerem, R.M., 1992, "Vascular Fluid Mechanics, the Arterial Wall, and Aterosclerosis," Journal of Biomechanical Engineering Transaction ASME, 114, pp. 274~282 https://doi.org/10.1115/1.2891384
  2. Zendehbudi, G.R. and Moayeri, M.S., 1999, "Comparison of Physiological and Simple Pulsatile Flows Through Stenosed Arteries," Journal of Biomechanics, 32, pp. 959~965 https://doi.org/10.1016/S0021-9290(99)00053-6
  3. Giddens, D.P., Zarins, C.K. and Glagov, S., 1993, "The Role of Fluid Mechanics in the Localization and Detection of Atherosclerosis," Journal of Biomechanical Engineering Transaction ASME, 115, pp. 588~594 https://doi.org/10.1115/1.2895545
  4. Mittal, M., Simmons, S.P., and Udaykumar, H.S., 2001, "Application of Large-Eddy Simulation to the Study of Pulsatile Flow in a Modeled Arterial Stenosis," Journal of Biomechanical Engineering Transaction ASME, 123, pp. 325~332 https://doi.org/10.1115/1.1385840
  5. Downing, J.M., and Ku, D.N., 1997, "Effects of Frictional Losses and Pulsatile Flow on the Collapse of Stenotic Arteries," Journal of Biomechanical Engineering Transaction ASME, 119, pp. 317~324 https://doi.org/10.1115/1.2796096
  6. Siegel, J.M. and Markou, C.P., 1994, "A Scaling Law for Wall Shear Rate Through an Arterial Stenosis," Journal of Biomechanical Engineering Transaction ASME, 116, pp. 446~451 https://doi.org/10.1115/1.2895795
  7. Lee, K.W. and Xu, X.Y., 2002, "Modelling of Flow and Wall Behaviour in a Mildly Stenosed Tube," Medical Engineering & Physics, 24, pp. 575~586 https://doi.org/10.1016/S1350-4533(02)00048-6
  8. Taewon Seo, Levanto G. Schachter, Abdul I. Barakat, 2005, "Computational Study of Fluid Mechanical Disturbance Induced by Endovascular Stents," Annals of Biomedical Engineering, Vol. 33, No. 4, pp. 444~456 https://doi.org/10.1007/s10439-005-2499-y
  9. Gidden, D.P., Zarins, C.K., Glagov, S., 1993, "The Role of Fluid Mechanics in the Localization and Detection of Atherosclerosis," Journal of Biomechanical Engineering Transaction ASME, 115, pp. 588~594 https://doi.org/10.1115/1.2895545
  10. Fry, D. L., 1972, “Response of the Arterial Wall to Certain Physical Factors. Atherogenesis: Initiating Factors,” A Ciba Foundation Symp., ASP, Amsterdam, The Neterlands, pp. 40~83
  11. Ku, D. N., Giddens, D. P., Zarins, C. K. and Glagov, S., 1985, “Pulsatile Flow and Atherosclerosis in the Human Carotid Bifurcation. Positive Correlation Between Plague Location and Low and Oscillating Shear Stress,” Arteriosclerosis, pp. 293~302
  12. Taewon Seo, Taedong Kim, Abdul I. Barakat, 2005, "Stent Design Using Computational Fluid Dynamics," Trans. of the KSME B, Vol. 29, No. 9, pp. 1042~1048 https://doi.org/10.3795/KSME-B.2005.29.9.1042