The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)
- Volume 21 Issue 2
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- Pages.1-18
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- 2008
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
Effects of Galgeunhaegitang-gamibang Administration along with Samhwangseze-gamibang on Atopic Dermatitis of NC/Nga Mice
갈근해기탕가미방(葛根解肌湯加味方)과 삼황세제가미방(三黃洗劑加味方) 병용이 NC/Nga 생쥐의 아토피 피부염에 미치는 영향
Abstract
Objectives: Galgeunhaegitang-gamibang(GH) and Samhwangseze-gamibang(SG) has been known that they are helpful for treatment of atopic dermititis clinically, but there is no report about the effect of GH and SG. So, author aimed to investigate the effects of GH and SG on atopic dermititis of NC/Nga mice. Methods : NC/Nga mice were divide into three group : normal, control, and experimental group. Atopic dermatitis was induced in the control and experimental group by spreading DNCB. Then GH was orally administered three times in a week for 8 weeks to the experimental group and SG was spreaded two times in a day for 8 weeks to the experimental group, while the control group was given normal saline. We observed changes of clinical skin severity score, serum IgE, IL-4, IL-4, IL-5, IL-6, IgM, IgGl,
Keywords
- Galgeunhaegitang-gamibang;
- Samhwangseze-gamibang;
- External treatment;
- Atopic dermatitis;
- NC/Nga mice