Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Case-Control Study on Electrolytes as a Risk Factor of Stroke

뇌졸중 위험지표로서의 전해질 수치에 대한 환자;대조군 연구

  • Kim, Min-Ji (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kang, Kyung-Won (Department of Medical Research, Korea Institute of Oriental Medicine) ;
  • Yu, Byeong-Chan (Department of Medical Research, Korea Institute of Oriental Medicine) ;
  • Choi, Sun-Mi (Department of Medical Research, Korea Institute of Oriental Medicine) ;
  • Kang, Ji-Sun (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Moon, Seung-Hee (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Lee, Jae-Hwi (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Yoon-Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol, In-Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 김민지 (대전대학교부속한방병원 심계내과학교실) ;
  • 강경원 (한국한의학연구원 의료연구부) ;
  • 유병찬 (한국한의학연구원 의료연구부) ;
  • 최선미 (한국한의학연구원 의료연구부) ;
  • 강지선 (대전대학교부속한방병원 심계내과학교실) ;
  • 문승희 (대전대학교부속한방병원 심계내과학교실) ;
  • 이재휘 (대전대학교부속한방병원 심계내과학교실) ;
  • 김윤식 (대전대학교부속한방병원 심계내과학교실) ;
  • 설인찬 (대전대학교부속한방병원 심계내과학교실)
  • Published : 2008.08.25
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Abstract

This study was aimed to investigate the electrolytes and its relationship with acute stroke patients in each stroke type by case-control study. 217 patients with first-ever acute stroke within 2 weeks as the case group(Cases), 146 people without four major risk factors(hypertension, diabetes mellitus, hyperlipidema and ischemic heart disease) as the healthy control group(Normals), and 160 people as the general control group(Controls) were recruited at the Stroke Medical Center in Daejeon University Oriental Medicine Hospital from july 2005 to march 2007 for this case-control study. We analyzed the odds ratio of electrolytes in binary logistic analysis and evaluated each stroke type and general characteristics such as age, sex etc. The level of sodium(Na+) and potassium(K+) were significantly lower in LAA, SVO type of ischemic stroke and hemorrhagic stroke. But the level of chloride(Cl-) had no significant relation with stroke occurance. In this study we demonstrated that low sodium(Na+) and potassium(K+) have an influence on stoke occurance than chloride(Cl-). And we think that the electrolytes must be considered in risk factors of ischemic stroke in Korean and more prospective studies are needed.

Keywords

References

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