The Korea Journal of Herbology (대한본초학회지)
- Volume 23 Issue 3
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- Pages.93-102
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- 2008
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Ethanol Extract of Forsythiae Fructus Inhibits the Production of Inflammatory Mediators in LPS-stimulated BV-2 Microglial Cells
연교 추출물의 Microglia에서 LPS에 의해 유도되는 염증매개물질 생성 억제 효과
- Kim, Sung-Yun (Department of Herbology, College of Oriental Medicine, Dongguk University) ;
- Park, Yong-Ki (Department of Herbology, College of Oriental Medicine, Dongguk University, Oriental Medicine Drug R&D Center, College of Oriental Medicine, Dongguk University)
- Published : 2008.09.30
Abstract
Objectives : Forsythiae Fructus (Forsythia koreana Nakai) has been used anti-inflammatory, diuretics, antidote, and antibacterials in traditional herbal medicine. The present study is focused on the inhibitory effect of Forsythiae Fructus ethanol extract (FF-E) on the production of inflammatory mediators such as NO, iNOS and proinflammatory cytokines (
Keywords
- Forsythiae Fructus;
- microglia;
- inflammation;
- nitric oxide;
- pro-inflammatory cytokine;
- neurodegenerative disease