생약학회지 (Korean Journal of Pharmacognosy)

  • 제39권3호
  • /
  • Pages.179-185
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  • 2008
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  • 0253-3073(pISSN)
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  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

패턴분석법에 의한 대황의 비교 연구

Comparative Study of the Rhei Rhizoma by Pattern Analysis

  • Kang, Jong-Seong (College of Pharmacy, Chungnam National University) ;
  • Park, Ki-Ju (College of Pharmacy, Chungnam National University) ;
  • Wu, En-Qi (College of Pharmacy, Chungnam National University) ;
  • Lee, Eun-Sil (College of Pharmacy, Chungnam National University) ;
  • Hwang, Gwi-Seo (College of Oriental Medicine, Kyungwon University) ;
  • Lee, Hyun-Sun (Korea Research Institute of Bioscience & Biotechnology) ;
  • Kim, Young-Ho (College of Pharmacy, Chungnam National University)
  • 발행 : 2008.09.30
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초록

Three species, such as Rheum palmatum L., R. tanguticum Maxim. and R. officinale Baillon are recognized as the source plants of Rhei Rhizoma in Korean Pharmacopeia. However, other herbal sources such as R. undulatum L. and Rumex crispus L. have been often misused as Rhei Rhizoma. A pattern analysis method to discriminate Rhei Rhizoma in Korean Pharmacopeia from other herbal plants using HPLC and TLC chromatograms was developed. The multivariate peak data of the chromatograms of methanol extracts of Rhei Rhizoma were used for hierarchical clustering analysis, principal components analysis and similarity calculation. Besides of the statistic analysis, TLC patterns of samples could be used as criteria of the discrimination. The developed pattern analysis method was specific and could be readily utilized for comprehensive evaluation of Rhei Rhizoma.

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