Tuberculosis and Respiratory Diseases

  • 제65권1호
  • /
  • Pages.37-40
  • /
  • 2008
  • /
  • 1738-3536(pISSN)
  • /
  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
권호 표지

소세포폐암에 동반된 미세변화 신증후군 1예

A Case of the Minimal Change Nephropathy Associated with Small Cell Lung Cancer

  • 고광일 (국민건강보험공단 일산병원 내과) ;
  • 송민근 (국민건강보험공단 일산병원 내과) ;
  • 신동엽 (국민건강보험공단 일산병원 내과) ;
  • 김동현 (국민건강보험공단 일산병원 내과) ;
  • 김찬호 (국민건강보험공단 일산병원 내과) ;
  • 한창훈 (국민건강보험공단 일산병원 내과) ;
  • 이선민 (국민건강보험공단 일산병원 내과) ;
  • 최윤정 (국민건강보험공단 일산병원 병리과) ;
  • 김정주 (국민건강보험공단 일산병원 내과)
  • Ko, Kwang Il (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Song, Min Keun (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Shin, Dong Yeob (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Kim, Dong Hyun (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Kim, Chan Ho (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Han, Chang Hoon (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Lee, Sun Min (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Choi, Yoon Jung (Department of Pathology, National Health Insurance Corporation Ilsan Hospital) ;
  • Kim, Chong Ju (Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital)
  • 투고 : 2008.05.09
  • 심사 : 2008.06.17
  • 발행 : 2008.07.30
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초록

본 증례는 소세포폐암에 동반된 미세변화 신증후군에 대한 국내 첫 번째 보고이며, 흉막여출액에 의한 호흡곤란과 말초부종 등 미세변화 신증훈군의 증상 발현에 의해 내원하여 잠재암이 발견된 경우이다. 본 증례를 통하여 성인의 경우 막성신병증 뿐만 아니라 미세변화 신증후군이라도 초기진단 시 원인질환으로 종양의 가능성을 고려해야 한다는 것을 경험하게 되었다.

Nephrotic syndrome is a relatively rare complication of malignancy. A few cases of nephrotic syndrome accompanying Hodgkin's disease, non-Hodgkin lymphoma, leukemia and other malignancies have been reported since the first case of the nephrotic syndrome associated with extrarenal malignancy was reported in 1922. Hodgkin's disease and solid tumors are known to be the most common malignancies accompanying nephrotic syndrome. The pathologic findings of kidney in patients with Hodgkin's disease commonly show minimal change nephropathy. Membranous glomerulonephropathy is the most common pathologic feature in patients with solid tumors. Although membranous glomerulonephropathy related to small cell lung cancer has rarely been reported in Korea, minimal change nephropathy accompanying small cell lung cancer has never been reported. We present here a case of a 70 year-old male with minimal change nephropathy that was related to small cell lung cancer. We detected small cell lung cancer during the diagnosis work-up of nephrotic syndrome. We suggest that nephrotic syndrome can be a manifestation of underlying malignancy.

키워드

참고문헌

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