Intra-arterial Direct Prostaglandin Infusion Combined with Lower Limb Arterial Bypass Graft and Lumbar Sympathectomy for Treating Buerger's Disease

버거씨 병(Buerger's Disease) 환자에서 하지지 동맥 우회로술 및 교감신경 차단술과 함께 이용된 동맥 내 프로스타글란딘 직접 투여

  • Yie, Kil-Soo (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kangwon National University, Clinical Research Institute of Kangwon National University Hospital) ;
  • Ryu, Se-Min (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kangwon National University, Clinical Research Institute of Kangwon National University Hospital) ;
  • Cho, Seong-Joon (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Kangwon National University, Clinical Research Institute of Kangwon National University Hospital) ;
  • Lee, Seo-Young (Department of Neurology, College of Medicine, Kangwon National University, Clinical Research Institute of Kangwon National University Hospital)
  • 이길수 (강원대학교 의과대학 흉부외과학교실, 강원대학교병원 임상의학연구소) ;
  • 류세민 (강원대학교 의과대학 흉부외과학교실, 강원대학교병원 임상의학연구소) ;
  • 조성준 (강원대학교 의과대학 흉부외과학교실, 강원대학교병원 임상의학연구소) ;
  • 이서영 (강원대학교 의과대학 신경과학교실, 강원대학교병원 임상의학연구소)
  • Published : 2008.08.05

Abstract

The incidence of the Buerger's disease is higher for the far-East Asian population that for western people, but the surgical outcomes have been documented to be unsatisfactory. So, more aggressive and multi-focused treatment modalities should be warranted such as stopping smoking or intravenous vasodilator infusion with surgery. We report here on a successful surgical case of intra-arterial direct infusion of Prostaglandin E1 concomitant with surgical bypass and lumbar sympathectomy to treat Buerger's disease.

서구인에 비해 동양인, 특히 극동지방의 버거씨 발병률은 높으나 우회로술 단독만의 성적은 아직 만족할 만하지 못하다고 알려져 있다. 따라서 우회론수술과 함께 교감신경 차단술, 금연, 정맥 내 혈관 확장제 투여 등의 보다 적극적이고 다양한 치료법이 요구되고 있다. 본 논문은 49세의 버거씨병 환자에게 복제정맥을 이용한 대퇴동맥-슬와동맥간 우회로술 및 교감 신경 차단술과 함께 동맥 내(intra-arterial) 프로스타글란딘 투여를 시행한 증례이다.

Keywords

References

  1. Jeffry WO. Thromboangitis obliterans: rutherford. Vascular Surgery. 6th ed. Philadelphia: Elsevier Saunders Co. 2005.
  2. Matsushita M, Nishikimi N, Sakurai T, Nimura Y. Decrease in prevalence of Buerger's disease in Japan. Surgery 1998;124:498-502. https://doi.org/10.1016/S0039-6060(98)70095-9
  3. Park JS, Kim KU. Buerger's disease in Korea. Korean J Vasc Surg 2005;21:105-12.
  4. Shionoya S. Buerger's disease: Diagnosis and management. Cardiovasc Surg 1993;1:207-15.
  5. De Giacomo T, Rendina EA, Venuta F. Thoracoscopic sympathectomy for symptomatic arterial obstruction of the upper extremities. Ann Thorac Surg 2002;74:885-8. https://doi.org/10.1016/S0003-4975(02)03806-7
  6. Okuda Y, Kitajima T. The effects of combined sympathetic block and intravascular infusion of prostaglandin E1 on brachial arterial blood flow in dogs. Anesth Analg 1999; 89:1514-6. https://doi.org/10.1097/00000539-199912000-00037
  7. Grant SM, Goa KL. Iloprost. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential on peripheral vascular disease, myocardial ischemia andd extracorporeal circulation procedures. Drugs 1992;43: 889-95. https://doi.org/10.2165/00003495-199243060-00008
  8. The European TAO Study Group. Oral iloprost in the treatment of thromboangitis obliterans (Buerger' s disease): a double-blind, radomised, placebo-controlled trail. Euro J Vasc Surg 1998;15:300-6. https://doi.org/10.1016/S1078-5884(98)80032-4