Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Analysis of SRY-negative XX True Hermaphroditism in an English Cocker Spaniel

  • Jang, Goo (Department of Theriogenology & Biotechnology, College of Veterinary Medicine, Seoul National University) ;
  • Byeon, Ye-Eun (Department of Veterinary Surgery, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Min-Kyu (Department of Animal Science and Biotechnology College of agricultural life Science Chungnam National University) ;
  • Koo, Ok-Jae (Department of Theriogenology & Biotechnology, College of Veterinary Medicine, Seoul National University) ;
  • Lee, Byeong-Chun (Department of Theriogenology & Biotechnology, College of Veterinary Medicine, Seoul National University)
  • Published : 2008.06.30
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Abstract

SRY gene is normally responsible for testis induction, yet testis development can occur in the absence of SRY. In here, we analyzed the SRY-negative sex reversal in cocker spaniel, at 1.5 year-old. The attacked dog was suffered from enlarged clitoris, and resulted in disorder of urination. By surgically approach, enlarged clitoris and one testis, which are apparently seen, are removed. Additionally, thorough the abdomen surgery, uterus and ovary-like mass were removed. The dog had XX, chromosome, showed negative for SRY-gene, and the mass had the ovary-testis structure. In other words, based on the macroscopic, cytogenic, and histological study, we can diagnose the cocker spaniel as SRY-negative sex reversal.

Keywords

References

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