Korean Journal of Fisheries and Aquatic Sciences (한국수산과학회지)

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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Antimicrobial Activities of Alkyl Gallates Alone and in Combination with Antibiotics Against the Fish Pathogenic Bacteria Edwardsiella tarda and Vibrio anguillarum

알킬갈레이트 유도체의 어병세균 Edwardsiella tarda와 Vibrio anguillarum에 대한 항균활성 및 항생제와의 병용효과

  • Kang, So-Young (Division of Food Science and Aqualife Medicine, Chonnam National University) ;
  • Kang, Ji-Young (Division of Food Science and Aqualife Medicine, Chonnam National University) ;
  • Kim, Su-Yeon (Division of Food Science and Aqualife Medicine, Chonnam National University) ;
  • Kim, Do-Hyung (Division of Food Science and Aqualife Medicine, Chonnam National University) ;
  • Oh, Myung-Joo (Division of Food Science and Aqualife Medicine, Chonnam National University)
  • 강소영 (전남대학교 식품.수산생명의학부) ;
  • 강지영 (전남대학교 식품.수산생명의학부) ;
  • 김수연 (전남대학교 식품.수산생명의학부) ;
  • 김도형 (전남대학교 식품.수산생명의학부) ;
  • 오명주 (전남대학교 식품.수산생명의학부)
  • Published : 2008.06.30
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Abstract

Methyl gallate isolated from bark of the tree Rhus verniciflua Stokes has significant antimicrobial activity against the fish pathogenic bacteria Edwardsiella tarda and Vibrio anguillarum. To evaluate the antimicrobial activity of gallate derivatives, eight alkyl gallates were tested. Ethyl gallate and propyl gallate had the highest activities, with MICs of $15.6-31.3{\mu}g/mL$ against E. tarda. For V. anguillarum, propyl gallate and butyl gallate were highly effective, with MICs of $7.81-31.3{\mu}g/mL$. When used in combination with antibiotics, methyl gallate exhibited synergistic effects with oxytetracycline against E. tarda and with norfloxacin against V. anguillarum. These results suggest that short-chain alkyl gallates can be used as alternatives to antibiotics against the fish pathogenic bacteria.

Keywords

References

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