Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

Bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs : pilot study

성견의 열개형 골결손 부위에 골형성 유도술식을 동반한 임플란트 식립 후의 골형성 : pilot study

  • Jeong, Ji-Yun (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration) ;
  • Sohn, Joo-Yeon (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration) ;
  • Chai, Kyung-Jun (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration) ;
  • Kim, Sung-Tae (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration) ;
  • Chung, Sung-Min (Dentium Co.) ;
  • Lee, In-Seop (Institute of Physics & Applied Physics, and Atomic-scale Surface Science Research Center, Yonsei University) ;
  • Cho, Kyoo-Sung (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration) ;
  • Kim, Chong-Kwan (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration) ;
  • Choi, Seong-Ho (Department of Periodontology, College of Dentistry, Yonsei University, Research institute for Periodontal Regeneration)
  • 정지윤 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 손주연 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 채경준 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김성태 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 정성민 ((주) 덴티움) ;
  • 이인섭 (연세대학교 초미세표면과학 연구센터) ;
  • 조규성 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 김종관 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소) ;
  • 최성호 (연세대학교 치과대학 치주과학교실, 치주조직재생연구소)
  • Published : 2008.06.30
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Abstract

Purpose: Guided bone regeneration(GBR) has emerged as a treatment in the management of osseous defects associated with dental implants. But several studies have reported different degrees of success of guided bone regeneration, depending upon the type of barrier selected, presence or absence of an underlying graft material, types of graft material, feasibility of technique, and clinician's preference. The aim of the present study was to evaluate bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs. Material and Methods: Standardized buccal dehiscence defects($3{\times}5\;mm$) were surgically 2 Mongrel dog's mandibles, each 8 SLA surface, 8 anodizing surface implants. Each buccal dehiscence defect received flap surgery only(no treatment, control), $Cytoflex^{(R)}$ membrane only, Resolut $XT^{(R)}$ membrane only, Resolut $XT^{(R)}+Osteon^{TM}$. Animals were sacrificed at 8 weeks postsurgery and block sections were harvested for histologic analysis. Resuts: All experimental group resulted in higher bone formation than control. Resolut $XT^{(R)}+Osteon^{TM}$ group resulted appeared highest defect resolution. There was no difference between SLA and anodizing surface, nonresorbable and resorbable membrane. Conclusion: GBR results in rapid and clinically relevant bone closure on dehiscence defects of the dental implants.

Keywords

References

  1. Dahlin C, Lekholm U, Linde A. Membrane-induced bone augmentation at titanium implants. A report on ten fixtures followed form 1 to 3 years after lodaing. Int J Periodontics Restorative Dent 1991;11:273-281
  2. Nyman s, Lang NP, Buse D et al. Bone regeneration adjacent to titanium dental implants using guided tissue regeneraion: A report of two cases. Int J Oral Maxiollofac Implants 1990;5:9-14
  3. Hammerle. A systematic review of the survival of implants in bone sites augmented with barrier membranes in partially edentulous patients. J Clin Periodontol 2002;29(suppl. 3):226-231 https://doi.org/10.1034/j.1600-051X.29.s3.14.x
  4. Simion M, Scarano A, Gionso L et al. Guided bone regeneration using resorbable and nonresorbable membranes; A comparative histological study in humans. Int J Oral Maxillovac Implants 1996;11:735-42
  5. Rosen P, Reynolds MA. Guided bone regeneration for dehiscence and fenetration defects on implants using an absorbable polymer barrier. J Periodontol 2001;72:250-6 https://doi.org/10.1902/jop.2001.72.2.250
  6. Selvig KA, Kersten BG, Chamberlain AD, Wikesjo UM & Nilveus RE. Regenerative surgery of intrabony periodontal defects using ePTFE barrier membranes: scanning electron microscopic evaluation of retrieved membrane vs clinical healing. J Periodontol 1992;63:974-978 https://doi.org/10.1902/jop.1992.63.12.974
  7. Tempro PJ, Nalbandian J. Colonization of retrieved polytetrafluroethylene membranes: morphological and microbiological observations. J Periodontol 1993:64:162-168 https://doi.org/10.1902/jop.1993.64.3.162
  8. Simion M, Baldoni M, Rossi P, Zaffe D. A comparative study of the effectiveness of e-PTFE membranes with and without early exposure during the healing period. Int J Periodontics & Restorative Dent 1994;14:166-180
  9. Becker W, Becker BE, Handlesman M et al. Bone formation at dehisced dental implant sites treated with implant augmentation material: a pilot study in dogs. Int J Periodontics Restorative Dent 1990;10:92-101
  10. Hockers T, Abensur D, Valentini P, Legrand R, Hammerle CH. The combined use of bioresorbable membranes and xenografts or autografts in the treatment of bone defects around implants. a study in beagle dogs. Clin Oral Implants Res 1999;10:487-498 https://doi.org/10.1034/j.1600-0501.1999.100607.x
  11. Jovanovic & Nevins. Bone formation utilizing titanium-reinforced barrier membrane. Int J Periodontics Restorative Dent 1995;15:56-69
  12. Buser. Localized ridge augmentation using GBR. Int J Periodontics Restorative Dent 1993;64:925-33
  13. Schierano G, Canuto RA, Navone R et al. Biological factors involved in the osseointegration of oral titanium implants with different surfaces. J Periodontol 2005;76:1710-1720 https://doi.org/10.1902/jop.2005.76.10.1710
  14. Schwartz Z, Lohmann CH, Oefinger J et al. Implant surface characteristics modulate differentiation behavior of cells in the osteoblastic lineage. Adv Dent Res 1999;13:38-48 https://doi.org/10.1177/08959374990130011301
  15. Albrektsson T, Wennerberg A. Oral impant surfaces: part 2-review focusing on clinical knowledge of different surface. Int J Prosthodont 2004;17:544-564
  16. Cho KS, Choi SH, Han KH et al. Alveolar bone formation at dental implant dehiscence defects following guided bone regeneration and xenogeneic freeze-dried demineralized bone matrix. Clin Oral Implants Res 1998;9:419-428 https://doi.org/10.1034/j.1600-0501.1996.090607.x
  17. Kim YS, Kim TG, Jung UW et al. Histomorphology on healing of the chitosan membrane and b-TCP on dental implant dehiscence defects in dogs. Key engineering materials 2006;309-311:255-258 https://doi.org/10.4028/www.scientific.net/KEM.309-311.255
  18. Dahlin C. Lekholm U, Becker W et al. Treatment of fenestration and dehiscence bone defect around oral implants using the guided tissue regeneration technique: a prospective multicenter study. Int J Oral Maxillofac Implants 1995;10:312-8
  19. Becker W, Schenk R, Higuchi K, Lekholm U, Becker BE. Variation in bone regeneration adjacent to implants augmented with barrier membranes alone or with demineralized freeze-dried bone or autologous grafts: a study in dogs. Int J Oral Maxillofac Implants;1995;143-154
  20. Ofer Moses, Sandu Pitaru, Zvi Artzi, Carlos E, Nemcovsky. Healing of dehiscence type defects in implants placed together with different barrier membranes: a comparative clinical study. Clin Oral Implants Res 2005; 210-219 https://doi.org/10.1111/j.1600-0501.2004.01100.x
  21. Jovanovic SA, Spiekermann H, Richter EJ. Bone regeneration around titanium dental implants in dehisced defect sites: a clinical study. Int J Oral & Maxillofac Implants 1992;7:233-245
  22. Cordaro L, Amade DS, Cordaro M. Clinical results of alveolar ridge augmentation with mandibular block bone grafts in partially edentulous patients prior to implant placement. Clin Oral Implants Res 2002;13:103-111 https://doi.org/10.1034/j.1600-0501.2002.130113.x
  23. Buser D, Bragger U, Lang NP, Nyman S. Regeneration and enlargement of jaw bone using guided tissue regeneration. Clin Oral Implants Res 1990;1:22-32 https://doi.org/10.1034/j.1600-0501.1990.010104.x
  24. Hjorting-Hansen E, Worsaae N, Lemmons J. Histologic response after implantation of porous hydroxyapatite ceramic in humans. Int J Oral and Maxillofac Implants 1992;7:255-263
  25. Wolfe LA, Hobkirk JA. Bone response to a matched modulus endosseous implant material. Int J Oral and Maxillofac Implants 1989;4:311-320
  26. Hjorting Hansen. Histologic response after implantation of porous hydroxylapatite ceramic in human. Int J Maxillofac Implants 1990;5:255-263