Journal of Periodontal and Implant Science

  • 제38권2호
  • /
  • Pages.179-190
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  • 2008
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  • 2093-2278(pISSN)
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  • 2093-2286(eISSN)
대한치주과학회 (Korean Academy of Periodontology)
권호 표지

무기인산염 함유 이상성 인산칼슘이 외방성 수직골 형성에 미치는 영향

The effect of micro-macroporous biphasic calcium phosphate incorporated with polyphosphate on exophytic bone regeneration

  • 김동환 (경희대학교 치의학전문대학원 치주과학교실) ;
  • 권영혁 (경희대학교 치의학전문대학원 치주과학교실) ;
  • 박준봉 (경희대학교 치의학전문대학원 치주과학교실) ;
  • 정종혁 (경희대학교 치의학전문대학원 치주과학교실) ;
  • 허익 (경희대학교 치의학전문대학원 치주과학교실)
  • Kim, Dong-Hwan (Department of Periodontology, School of Dentistry, Kyung Hee University) ;
  • Kwon, Young-Hyuk (Department of Periodontology, School of Dentistry, Kyung Hee University) ;
  • Park, Joon-Bong (Department of Periodontology, School of Dentistry, Kyung Hee University) ;
  • Chung, Jong-Hyuk (Department of Periodontology, School of Dentistry, Kyung Hee University) ;
  • Herr, Yeek (Department of Periodontology, School of Dentistry, Kyung Hee University)
  • 발행 : 2008.06.30
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초록

Purpose: In this study, the effect of micro-macroporous biphasic calcium phosphate(MBCP) incorporated with inorganic polyphosphate for bone regeneration in the calvaria of rabbit was evaluated. Materials and Methods: The procedure of guided bone regeneration was performed with titanium reinforced expanded polytetrafluoroethylene(TR-ePTFE) membrane. Four animal groups were compared : 1) TR-ePTFE membrane for negative control group, 2) TR-ePTFE membrane filled with MBCP for positive control group, 3) TR-ePTFE membrane filled with MBCP soaked in 4% inorganic polyphosphate for experimental group I, and 4) TR-ePTFE membrane filled with MBCP soaked in 8% inorganic polyphosphate for experimental group II. Results: 1. Negative control group showed the highest new bone formation at 16 weeks. 2. Positive control group showed the smallest new bone formation compared to other groups. 3. 8% inorganic polyphosphate induced more volume of bone formation, otherwise experimental group II did not show significant difference compared to negative control group. Conclusion: These results suggest that inorganic polyphosphate has a promoting effect on bone regeneration, possibly by enhancing osteoconductivity of the carrier and by increasing osteoinductivity of the defected alveolar bone tissue.

키워드

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