생명과학회지 (Journal of Life Science)

  • 제18권7호
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  • Pages.947-951
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  • 2008
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  • 1225-9918(pISSN)
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  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
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알코올 급여 흰쥐의 혈중 성호르몬 및 아연 농도에 미치는 아연 고함유 효모 Saccharomyces cerevisiae 급여의 영향

Effect of Zinc-Enriched Yeast Supplementation on Serum Zinc and Testosterone Concentrations in Ethanol Feeding Rats

  • 차재영 (대선주조(주) 기술연구소) ;
  • 허진선 (동아대학교 생명자원과학대학 생명공학과) ;
  • 박보경 (동아대학교 생명자원과학대학 생명공학과) ;
  • 조영수 (동아대학교 생명자원과학대학 생명공학과)
  • Cha, Jae-Young (Technical Research Institute, Daesun Distilling Co. Ltd.) ;
  • Heo, Jin-Sun (Department of Biotechnology, College of Natural Resources and Life Science, Dong-A University) ;
  • Park, Bo-Kyung (Department of Biotechnology, College of Natural Resources and Life Science, Dong-A University) ;
  • Cho, Young-Su (Department of Biotechnology, College of Natural Resources and Life Science, Dong-A University)
  • 발행 : 2008.07.30
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초록

아연은 많은 생리학적인 기능을 가지는 필수미량 원소로, 특히 성기능에 있어서 중요한 역할을 하는 것으로 잘 알려져 있다. 열대 과일 Rambutan으로부터 분리된 아연 고함유 효모의 미네랄 성분은 아연 306 ppm, K 28,640 ppm, Mg 2,342, Na 1,048 ppm, Ca 366 ppm, Fe 236 ppm 및 Mn 4 ppm이 함유되어 있었다. 혈청 중 성호르몬인 테스토스테론(testosterone) 농도는 정상군에 비해 에탄올 급여 실험군에서 감소 경향을 나타내었다. 에탄올 급여에 의한 성호르몬 테스토스테론의 농도 감소는 아연 고함유 효모 투여로 현저하게 증가하였다. 또한, 혈청 중 아연 함량에 에탄올 급여 실험군에서 감소경향을 보였고, 이러한 감소는 아연 고함유 효모 투여로 현저하게 증가하였다. 따라서, 에탄올 투여에 의한 혈중 아연 및 테스토스테론 농도의 감소효과는 아연 고함유 효모 투여로 상쇄되는 것으로 나타나 본 실험에 사용된 아연 고함유 효모는 성기능 관련 건강기능식품의 소재로서 산업적으로 유용하게 사용될 것으로 사료되어 진다.

Zinc is an essential trace element participating in many physiological functions and notably an important function for sperm physiology. Zinc-enriched yeast strain, Saccharomyces cerevisiae, isolated from tropical fruit rambutan. This strain contained 306 ppm zinc concentration and other components contained by K 28,640 ppm, Mg 2,342 ppm, Na 1,048 ppm, Ca 366 ppm, Fe 236 ppm and Mn 4 ppm. The serum concentration of testosterone was decreased in ethanol treatment rats. As compared with ethanol treated control rats, the zinc-enriched yeast strain supplementation showed significantly increased the testosterone concentration in serum. In addition, zinc concentration in serum was decreased in alcohol treatment, but this reduction was significantly increased by zinc-enriched yeast strain supplementation in ethanol feeding rats. These results indicate that zinc-enriched yeast Saccharomyces cerevisiae strain could play an important role in the sperm physiology by the marked elevation of serum testosterone concentration.

키워드

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