대한한의학회지 (The Journal of Korean Medicine)
- 제29권3호
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- Pages.1-10
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- 2008
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- 1010-0695(pISSN)
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- 2288-3339(eISSN)
세균을 이용한 십전대보탕 복귀돌연변이 시험
Bacterial Reverse Mutation Test of Sipjeondaebo-tang
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Ma, Jin-Yeul
(Korea Institue of Oriental Medicine) ;
- Huang, Dae-Sun (Korea Institue of Oriental Medicine) ;
- Lee, Nam-Hun (Korea Institue of Oriental Medicine) ;
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Ha, Hye-Kyung
(Korea Institue of Oriental Medicine) ;
- Yu, Young-Beob (Korea Institue of Oriental Medicine) ;
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Shin, Hyun-Kyoo
(Korea Institue of Oriental Medicine)
- 발행 : 2008.07.31
초록
Objectives: This study was to assess the toxicity of Sipjeondaebo-tang by bacterial reverse mutation test. Methods: In this study, to evaluate the bacterial reverse mutation of Sipjeondaebo-tang water-extract, the in vitro Ames test using Salmonella typhimurium (TA98, TA100, TA1,535, TA1,537) and Escherichia coli(WP2uvrA) were performed with Sipjeondaebo-tang water extract at the concentrations 0, 312, 625, 1250, 2500 and 5000