The Journal of Korean Medicine (대한한의학회지)
- Volume 29 Issue 3
- /
- Pages.1-10
- /
- 2008
- /
- 1010-0695(pISSN)
- /
- 2288-3339(eISSN)
Bacterial Reverse Mutation Test of Sipjeondaebo-tang
세균을 이용한 십전대보탕 복귀돌연변이 시험
- Ma, Jin-Yeul (Korea Institue of Oriental Medicine) ;
- Huang, Dae-Sun (Korea Institue of Oriental Medicine) ;
- Lee, Nam-Hun (Korea Institue of Oriental Medicine) ;
- Ha, Hye-Kyung (Korea Institue of Oriental Medicine) ;
- Yu, Young-Beob (Korea Institue of Oriental Medicine) ;
- Shin, Hyun-Kyoo (Korea Institue of Oriental Medicine)
- Published : 2008.07.31
Abstract
Objectives: This study was to assess the toxicity of Sipjeondaebo-tang by bacterial reverse mutation test. Methods: In this study, to evaluate the bacterial reverse mutation of Sipjeondaebo-tang water-extract, the in vitro Ames test using Salmonella typhimurium (TA98, TA100, TA1,535, TA1,537) and Escherichia coli(WP2uvrA) were performed with Sipjeondaebo-tang water extract at the concentrations 0, 312, 625, 1250, 2500 and 5000