Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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A Case of Sensory Neuronopathy Caused by Pyridoxine Intoxication

피리독신 중독에 의한 감각신경원병증 1예

  • Kim, Ji-Sun (Department of Neurology, Soon Chun Hyang University College of Medicine) ;
  • Lee, Kyung-Bok (Department of Neurology, Soon Chun Hyang University College of Medicine) ;
  • Roh, Hakjae (Department of Neurology, Soon Chun Hyang University College of Medicine) ;
  • Ahn, Moo-Young (Department of Neurology, Soon Chun Hyang University College of Medicine)
  • 김지선 (순천향대학교 의과대학 신경과학교실) ;
  • 이경복 (순천향대학교 의과대학 신경과학교실) ;
  • 노학재 (순천향대학교 의과대학 신경과학교실) ;
  • 안무영 (순천향대학교 의과대학 신경과학교실)
  • Received : 2008.05.22
  • Accepted : 2009.06.09
  • Published : 2008.06.30
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Abstract

Pyridoxine has been known as an essential cofactor in many important biological reactions of tissue metabolism including blood, skin, and central nervous system. Nowadays, vitamins are widely consumed because of the belief that they provide health benefits with no harm. We report a patient with sensory ataxia who had a 3-year history of excessive vitamin $B_6$ intake. Her clinical and electrodiagnostic findings were characteristic of sensory neuronopathy, which were probably caused by pyridoxine intoxication. Physicians should be aware of the toxicities of megavitamin therapy.

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