대한임상검사과학회지 (Korean Journal of Clinical Laboratory Science)
- 제40권2호
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- Pages.71-74
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- 2008
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- 1738-3544(pISSN)
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- 2288-1662(eISSN)
자연 유산 수태산물의 세포유전학적 분석
A Cytogenetic Analysis of Abortus with Spontaneous Abortion
- Oh, Hyun-Sook (Department of Clinical Laboratory Science, Wonkwang Health Science College) ;
- Hwang, Si-Mok (Department of Clinical Laboratory Science, Wonkwang Health Science College) ;
- Kwon, Kyung-Hun (Division of Research and Development, GenDix, Inc.)
- 발행 : 2008.12.31
초록
Chromosomal abnormalities of abortus have also been used to investigate the most common etiology of spontaneous abortion, but the frequency and the types of spontaneous abortions have also demonstrated considerable variation among in different countries and races. A cytogenetic analysis of 75 abortuses was performed at the GenDix, Inc. from January, 2006 to December, 2007. The frequency of chromosome abnormalities in abortus was 32.0% (24/75 cases). Among the chromosomal abnormalities, trisomy was 62.5% (15/24 cases) and the most frequent trisomy was trisomy 21 with 26.6% (4/15 cases). The average maternal age of normal and abnormal karyotypes was