한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제21권3호
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- Pages.82-93
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- 2008
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
비만세포에서의 창이자의 탈과립 및 pro-inflammatory cytokines 분비량에 미치는 영향
Xanthium strumarium suppresses degranulation and pro-inflammatory cytokines secretion on the mast cells
- Lyu, Ji-Hyo (Clinical Research Center of Oriental Medicine, Dongeui University) ;
- Yoon, Hwa-Jung (Department of Oriental Medicine, College of Oriental Medicine, Dongeui University) ;
- Hong, Sang-Hoon (Clinical Research Center of Oriental Medicine, Dongeui University) ;
- Ko, Woo-Shin (Clinical Research Center of Oriental Medicine, Dongeui University)
- 발행 : 2008.12.24
초록
Objective: Previously, the methanol extracts of the semen of Xanthium strumsrium could involved anti-inflammatory effects in lipopolysaccharide (LPS)-stimulated Raw 264,7 cells, We evaluated the anti-allergic effects of X. strumarium on rat basophilic leukemia (RBL-2H3) cells, Methodes : To investigate the effect of X. strumarium on the phorbol 12-myristate 13-acetate (PMA) and calcium ionophore A23187-induced RBL-2H3 cells. The effects of X. strumarium on the degranulation and the pro-inflammatory cytokines secretion and expression from RBL-2H3 cells were evaluated with
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