The Journal of Internal Korean Medicine (대한한방내과학회지)
- Volume 29 Issue 4
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- Pages.1025-1036
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- 2008
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- 1226-9174(pISSN)
The Effects of Gypsum on Streptozotocin-induced Diabetic Nephropathic Rats
석고(石膏)가 streptozotocin 으로 유발된 rat의 당뇨병성(糖尿炳性) 신증(腎症)에 미치는 영향(影響)
- Hong, Gwang-Hae (Dept. of Internal Medicine, College of Oriental Medicine, Dongshin University) ;
- Lee, Kwun-Ho (Dept. of Internal Medicine, College of Oriental Medicine, Dongshin University) ;
- Jeong, Gi-Hoon (Dept. of Internal Medicine, College of Oriental Medicine, Dongshin University) ;
- Kim, Young-Seong (Dept. of Internal Medicine, College of Oriental Medicine, Dongshin University) ;
- Lee, Hyun-Ju (Oriental Internal Medicine, Jein Hospital of Oriental Medicine)
- 홍광해 (동신대학교 한의과대학 신계내과학교실) ;
- 이권호 (동신대학교 한의과대학 신계내과학교실) ;
- 정기훈 (동신대학교 한의과대학 신계내과학교실) ;
- 김용성 (동신대학교 한의과대학 신계내과학교실) ;
- 이현주 (제인한방병원 한방내과)
- Published : 2008.12.31
Abstract
Objectives : The aim of present study was to investigate recovery effects of gypsum, which has been used clinically in diabetes therapy. Methods : We established three groups, normal, control, and gypsum, and assigned 6 rats to each group. The normal group was not treated by any process and fed normal saline. The control & gypsum groups were administered streptozotocin(STZ) to induce diabetes. Gypsum extract was orally administered to the gypsum group for 10 days. After 8 weeks, the rats were sacrificed and their body weight, 24hrs urinary protein excretion, glucose, albumin, BUN, creatinine, total-cholesterol, LDL-cholesterol, triglyceride in blood, level of glycation end-product (AGE) and transforming growth factor (