The Journal of Internal Korean Medicine (대한한방내과학회지)
- Volume 29 Issue 4
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- Pages.887-903
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- 2008
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- 1226-9174(pISSN)
Study about Herb-Drug Interaction for Cancer Patients
암 환자의 한약-양약 상호작용에 대한 고찰
- Bang, Sun-Hwi (East-West Cancer Center, Daejeon University) ;
- Han, Sung-Su (East-West Cancer Center, Daejeon University) ;
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Cho, Jung-Hyo
(East-West Cancer Center, Daejeon University) ;
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Lee, Yeon-Weol
(East-West Cancer Center, Daejeon University) ;
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Cho, Chong-Kwan
(East-West Cancer Center, Daejeon University) ;
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Yoo, Hwa-Seung
(East-West Cancer Center, Daejeon University)
- 방선휘 (대전대학교 둔산한방병원 동서암센터) ;
- 한성수 (대전대학교 둔산한방병원 동서암센터) ;
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조정효
(대전대학교 둔산한방병원 동서암센터) ;
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이연월
(대전대학교 둔산한방병원 동서암센터) ;
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조종관
(대전대학교 둔산한방병원 동서암센터) ;
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유화승
(대전대학교 둔산한방병원 동서암센터)
- Published : 2008.12.31
Abstract
Objectives : We present some opinions to reduce the risk of herb-drug interactions through scanning "About Herbs" of the Memorial Sloan Kettering Cancer Center Website. Methods : We searched the Memorial Sloan Kettering Cancer Center Website of About Herbs and investigated herb-drug interactions. Results : There are 237 herbs and 196 drugs on About Herbs. 81.1% of herbs have fewer than 2 interactions listed.: 86.3% of drugs fewer than 3 interactions. Especially, 13 herbs were reported to have interactions with inclusive chemoagents on About Herbs. Only L-theanine has positive interaction with inclusive chemoagents. The others have negative interactions with inclusive chemoagents. 12 single chemoagents were reported to have interactions with some herbs. Especially tamoxifen-black cohosh, methotrexate-glutamin and aldesleukin-Huang Chi have positive interactions to increase the effects of the chemoagent. Conclusions : We should urgently create a risk management system of herb-drug interactions and take note of the risk of herb-drug interactions. We should build up systemic, evidence-based informations on popular herbs used by Korean cancer patients and herb-drug interactions in oncology like About Herbs.