DOI QR코드

DOI QR Code

Clinical Outcomes after Percutaneous Vertebroplasty for Pathologic Compression Fractures in Osteolytic Metastatic Spinal Disease

  • Lim, Bong-Suk (Department of Neurosurgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science) ;
  • Chang, Ung-Kyu (Department of Neurosurgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science) ;
  • Youn, Sang-Min (Department of Neurosurgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Science)
  • Received : 2009.03.03
  • Accepted : 2009.05.31
  • Published : 2009.06.28

Abstract

Objective : Percutaneous vertebroplasty (VP) can provide immediate stabilization in pathologic fractures of spinal tumors. However, long term follow-up data in cases of pathologic fractures are lacking. The authors report follow-up results of VP in 185 pathologic fractures of 102 spinal tumor patients. Methods : Percutaneous VP was performed at 185 vertebral bodies of 102 patients from 2001 to 2007. Retrospective analysis was done with medical records and radiological data. The change of visual analogue score (VAS), vertebral body (VB) height and kyphotic angle were measured preoperatively and on postoperative one day and at 3, 6, and 12 months. Results : The patients were composed of metastatic spine tumors (81%) and multiple myeloma (19%). Involved spinal segments were between T6 and L5. Mean follow-up period was 12.2 months. VAS for back pain was 8.24 preoperatively, 3.59 (postoperative one day), 4.08 (three months) and 5.22 (one year). VB compression ratio changed from 21.33% preoperatively to 13.82% (postoperative one day), 14.36% (three month), and 16.04% (one year). Kyphotic angle changed from $15.35^{\circ}$ preoperatively to $12.03^{\circ}$ (postoperative one day), $13.64^{\circ}$ (three month), and $15.61^{\circ}$ (one year). Conclusion : Immediate pain relief was definite after VP in pathologic compression fracture of osteolytic spinal disease. Although VAS was slightly increased on one year follow-up, VP effect was maintained without significant change. These results indicate that VP could be a safe and effective procedure as a palliative treatment of the spinal tumor patients.

Keywords

Cited by

  1. Vertebroplasty for pain relief and spinal stabilization in multiple myeloma vol.31, pp.2, 2010, https://doi.org/10.1007/s10072-009-0197-5
  2. Impact of Pain Question Modifiers on Spine Augmentation Outcome vol.257, pp.2, 2009, https://doi.org/10.1148/radiol.10100237
  3. Continuous Multiple Vertebral Compression Fractures in Multiple Myeloma Patient vol.9, pp.1, 2009, https://doi.org/10.14245/kjs.2012.9.1.37
  4. Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective vol.54, pp.2, 2009, https://doi.org/10.3340/jkns.2013.54.2.151
  5. Vertebral Augmentation in Patients with Multiple Myeloma: A Pooled Analysis of Published Case Series vol.35, pp.1, 2009, https://doi.org/10.3174/ajnr.a3622
  6. Quality of life in patients with multiple myeloma treated with percutaneous vertebroplasty vol.13, pp.1, 2009, https://doi.org/10.1590/s1808-185120141301rc105
  7. Clinical efficacy of percutaneous vertebroplasty combined with intensity-modulated radiotherapy for spinal metastases in patients with NSCLC vol.8, pp.None, 2009, https://doi.org/10.2147/ott.s86270
  8. Patterns of Treatment for Metastatic Pathological Fractures of the Spine: The Efficacy of Each Treatment Modality vol.7, pp.4, 2015, https://doi.org/10.4055/cios.2015.7.4.476
  9. Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases vol.7, pp.None, 2009, https://doi.org/10.1038/s41598-017-07649-z
  10. A review and update of vertebral fractures due to metastatic tumors of various sites to the spine: Percutaneous vertebroplasty vol.10, pp.1, 2009, https://doi.org/10.1556/1646.10.2018.03
  11. Efficacy of percutaneous vertebroplasty treatment of spinal tumors : A meta-analysis vol.97, pp.3, 2018, https://doi.org/10.1097/md.0000000000009575
  12. How do vertebroplasty and kyphoplasty affect the quality of life of patients with multiple myeloma spinal metastasis? vol.30, pp.8, 2009, https://doi.org/10.1007/s00590-020-02721-3