Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
권호 표지

Cerebellar Ganglioglioma

  • Park, Seong-Ho (Division of Neurooncology and Skull Base Surgery, Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Kim, Ealmaan (Division of Neurooncology and Skull Base Surgery, Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine) ;
  • Son, Eun-Ik (Division of Neurooncology and Skull Base Surgery, Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine)
  • Published : 2008.03.18
Download PDF
⟨ Previous Next ⟩

Abstract

The location of ganglioglioma (GG) within the infratentorial compartment is unusual. The authors report a rare case of GG in the cerebellar hemisphere. A 12-year-old boy suffered from headache and gait disturbance. Neuroimaging studies demonstrated a large enhancing cerebellar mass with cystic components compressing the forth ventricle. After complete resection of the tumor, the patient became symptom free. Histological examination on the tumor disclosed glial cells and dysplastic ganglion cells. Although it is a rare tumor, in the appropriate clinical setting, a GG should be considered in the presence of a cerebellar mass with both solid and cystic components on magnetic resonance images in children.

Keywords

References

  1. Baussard B, Di Rocco F, Garnett MR, Boddaert N, Lellouch-Tubiana A, Grill J, et al : Pediatric infratentorial gangliogliomas : a retrospective series. J Neurosurg (4 Suppl) 107 : 286-291, 2007 https://doi.org/10.3171/ped.2007.107.4.286
  2. Blatt GL, Ahuja A, Miller LL, Ostrow PT, Soloniuk DS : Cerebellomedullary ganglioglioma : CT and MR findings. AJNR Am J Neuroradiol 16 : 790-792, 1995
  3. Hakim R, Loeffler JS, Anthony DC, Black PM : Gangliogliomas in adults. Cancer 79 : 127-131, 1997 https://doi.org/10.1002/(SICI)1097-0142(19970101)79:1<127::AID-CNCR18>3.0.CO;2-6
  4. Handa H, Yamagami T, Furuta M : An adult patient with cerebellar ganglioglioma. J Neurooncol 18 : 183-189, 1994 https://doi.org/10.1007/BF01328952
  5. Im SH, Chung CK, Cho BK, Wang KC, Yu IK, Song IC, et al : Intracranial ganglioglioma : preoperative characteristics and oncologic outcome after surgery. J Neurooncol 59 : 173-183, 2002 https://doi.org/10.1023/A:1019661528350
  6. Jang EW, Cho JH, Chang JH, Ahn JY : Cerebellar ganglioglioma in an old patient. J Korean Neurosurg Soc 42 : 53-55, 2007
  7. Johannsson JH, Rekate HL, Roessmann U : Gangliogliomas : pathological and clinical correlation. J Neurosurg 54 : 58-63, 1981 https://doi.org/10.3171/jns.1981.54.1.0058
  8. Kwon JW, Kim IO, Cheon JE, Kim WS, Chi JG, Wang KC, et al : Cerebellopontine angle ganglioglioma : MR Findings. AJNR Am J Neuroradiol 22 : 1377-1379, 2001
  9. Lu WY, Goldman M, Young B, Davis DG : Optic nerve ganglioglioma. Case report. J Neurosurg 78 : 979-982, 1993 https://doi.org/10.3171/jns.1993.78.6.0979
  10. Mesiwala AH, Kuratani JD, Avellino AM, Roberts TS, Sotero MA, Ellenbogen RG : Focal motor seizures with secondary generalization arising in the cerebellum. Case report and review of the literature. J Neurosurg 97 : 190-196, 2002 https://doi.org/10.3171/jns.2002.97.1.0190
  11. Milligan BD, Gainnini C, Link MJ : Gangliogliomas in the cerebellopontine angle in a child. Case report and review of the literature. J Neurosurg 107 (4 Suppl) : 292-296, 2007 https://doi.org/10.3171/ped.2007.107.4.292
  12. Mizuno J, Nishio S, Barrow DL, Davis PC, Tindall GT : Ganglioglioma of the cerebellum : case report. Neurosurgery 21 : 584-588, 1987 https://doi.org/10.1227/00006123-198710000-00029
  13. Nishizawa S, Yokoyama T, Ryu H, Ninchoji T, Shimoyama I, Satoh K, et al : Cerebellar ganglioglioma. Case report. Neurol Med Chir (Tokyo) 31 : 777-781, 1991 https://doi.org/10.2176/nmc.31.777
  14. Selch M, Goy B, Lee S, El-Sadin S, Kincaid P, Park SH : Gangliogliomas : experience with 34 patients and review of the literature. Am J Clin Oncol 21 : 557-564, 1998 https://doi.org/10.1097/00000421-199812000-00006
  15. Turgut M, Ozcan OE : Cerebellar ganglioglioma. Case report. J Neurosurg Sci 34 : 151-153, 1990
  16. Zentner J, Wolf HK, Ostertun B, Hufnagel A, Campos MG, Solymosi L, et al : Gangliogliomas : clinical, radiological and histopathological findings in 51 patients. J Neurol Neurosurg Psychiatry 57 : 1497-1502, 1994 https://doi.org/10.1136/jnnp.57.12.1497