Effects of Injinoryung-San on Alcoholic Hepatitis

인진오령산의 알콜성 간염에 미치는 영향

  • Hong, Su-Hyun (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Kwon, O-Sun (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Kim, Sang-Heon (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Kim, Hyo-Jin (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Kim, Ki-Tak (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Park, Sang-Eun (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Kim, Won-Il (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Kang, Chang-Wan (Department of Data Information Science, Dongeui University) ;
  • Cho, Jung-Hyo (Department of Internal Medicine, College of Oriental Medicine, Dongeui University) ;
  • Son, Chang-Gue (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Ryu, Woo-Sang (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Kyung-Nam (HVLS. Co. Ltd) ;
  • Hong, Sang-Hoon (Department of Internal Medicine, College of Oriental Medicine, Dongeui University)
  • Published : 2008.02.25

Abstract

This study was performed to investigate the effect of the extracts from Injinoryng-San on liver injury patients induced by alcohol. Injinoryung-San was recorded the drug for jaundice at Hwang-Je-Nae-Kyung. Twenty-seven patients who have intaked alcohol above 40 g, every day, 5 years, twenty-seventy ages were selected. After take a written consent, we divide them into experimental groups and control groups by double blind test. Each groups was evaluated every 2 weeks(2,4,6 weeks). After 2 weeks, Injinoryung-San groups significantly decreased GGT in comparison with control groups(p<0.05). After 4 weeks, Injinoryung-San groups significantly decreased MCV, GGT in comparison with control groups(p<0,05). After 6 weeks, Injinoryung-San groups significantly decreased MCV in comparison with control groups(p<0.05). Reviewing these experimental results, it appears that extracts of Injinoryung-San have pharmaceutical efficacy in GGT, MCV on liver injury patients induced by alcohol. But it has not efficacy in AST, ALT. According to drinking alcohol has becomes social problems, we should effort to make efficacious oriental medicines on alcoholic hepatitis.

Keywords

References

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