Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Isolation of Lipids from the Aerial Parts of Spathiphyllum cannifolium

스파티필름(Spathiphyllum cannifolium) 지상부로부터 지질화합물의 분리

  • Lee, Dae-Young (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Park, Ji-Hae (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Yoo, Jong-Su (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Song, Myoung-Chong (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Baek, Nam-In (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) ;
  • Lee, Youn-Hyung (Department of Horticultural Biotechnology, Kyung Hee University)
  • 이대영 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 박지해 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 유종수 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 송명종 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 백남인 (경희대학교 생명공학원 및 식물대사연구센터) ;
  • 이윤형 (경희대학교 원예생명공학)
  • Published : 2008.03.31
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Abstract

The aerial parts of Spathiphyllum cannifolium were extracted with 80% aqueous MeOH and the concentrated extract was partitioned with EtOAc, n-BuOH and $H_2O$, successively. From the EtOAc fraction, three compounds were isolated through the repeated silica gel, ODS, Sephadex LH-20 column chromatographies. From the results of physico-chemical data including NMR, MS and IR, the chemical structures of the compounds were determined as stigmasterol (1), $(2S)1-O-linolenoyl-2-0-myristoyl-3-0-{\beta}-D-galactopyranosyl-sn-glycerol$ (2) and stigmasterol glucoside (3). They were the first to be isolated from Spathiphyllum cannifolium.

스파티필름 지상부를 80% MeOH 용액으로 추출하고, 얻어진 추출물을 EtOAc, n-BuOH 및 $H_2O$로 용매 분획 하였다. 이 중 EtOAc 분획으로부터 silica gel, ODS 및 Sephadex LH-20 column chromatography로 정제하여 3종의 지질화합물을 분리 하였다. 각 화합물의 화학구조는 NMR, MS, 및 IR 등의 스펙트럼 데이터를 해석하여 stigmasterol (1), $(2S)1-O-linolenoyl-2-O-myristoyl-3-O-{\beta}-D-galactopyranosyl-sn-glycerol$ (2), stigmasterol glucoside (3)으로 동정하였다. 이 화합물들은 스파티필름에서 처음으로 분리 및 동정 되었다.

Keywords

References

  1. Ha, S. H. (1998) In Plants of Korean Flower Arrangement. Gwang-jin press, Seoul, Korea, pp. 57
  2. Lewis, J. A., Moore, C. J., Fletcher, M. T., Drew, Ri. A. and Kitching, W. (1988) Volatile compounds from the flowers of Spathiphyllum cannaefolium. Phytochemistry 27, 2755-2757 https://doi.org/10.1016/0031-9422(88)80656-3
  3. Yoo, J. S., Ahn, E. M., Bang, M. H., Song, M. J., Yang, H. J., Kim, D. H., Lee, D. Y., Chung, H. G., Jeong, T. S., Lee, K. T. Choi, M. S. and Baek, N. I. (2006) Steroids from the aerial parts of Aremisia princeps Pampanini. Korean J. Medicinal Crop Sci. 14, 273-277
  4. Murakami, N., Immamura, H., Morimoto, T., Ueda, T., Nagai, S., Sakakibara, J. and Yamada, N. (1991) Selective preparation of sn-1 and sn-2 lysogalactolipids by enzymatic hydrolysis using lipase (from Rhizopus arrhizus). Tetrahedron Lett. 32, 1331-1334 https://doi.org/10.1016/S0040-4039(00)79660-2
  5. Majinda, R. R. T., Waigh, R. D. and Waterman, P. G. (1997) Bufadienolides and other constituents of Urginea sanguinea. Planta Med. 63, 188-190 https://doi.org/10.1055/s-2006-957644
  6. Jeung, B. S. and Sin, M. K. (1990) In Hang Yak Dae Sa Jeun. Young Lim Sa, Seoul, Korea, p. 282
  7. Jeung, B. S. and Sin, M. K. (1990) In Hang Yak Dae Sa Jeun. Young Lim Sa, Seoul, Korea, p. 285
  8. Jung, J. H., Lee, C. O., Kim, Y. C. and Kang, S. S. (1996) New bioactive cerebrosides from Arisaema amurense. J. Nat. Prod. 59, 319-322 https://doi.org/10.1021/np960201+
  9. Gonda, R., Tomoda, M., Shimizu, N., Ohara, N., Takagi, H. and Hoshino, S. (1994) Characterization of an acidic polysaccharide with immunological activities from the tuber of Pinellia ternata. Biol. Pharm. Bull. 17, 1549-1553 https://doi.org/10.1248/bpb.17.1549
  10. Zhang, D. Y., Mori, M., Hall, I. H. and Lee, K. H. (1991) Anti-inflammatory agents. V. Amylose from Pinellia ternata. Int. J. Pharm. 29, 29-32 https://doi.org/10.3109/13880209109082845
  11. Liu, H., Guo, S., Shen, Y. and Li, X. (2004) Antioxidative effect of ${\beta}$-sitosterol in Pinellia ternata (Thunb.) Breit. Guangdong Yaoxueyuan Xuebao 20, 281-283
  12. Ghorab, A. H., Mahgoub, M. H., Bekheta, M. (2006) Effect of some bioregulators on the chemical composition of essential oil and its antioxidant activity of Egyptian carnation (Dianthus caryophyllus L.). J. Essent. Oil-Bearing Plants 9, 214-222 https://doi.org/10.1080/0972060X.2006.10643494
  13. Glisic, S. B., Misic, D. R., Stamenic, M. D., Zizovic, I. T., Asanin, R. M. and Skala, D. U. (2007) Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity, Food Chem. 105, 346- 352 https://doi.org/10.1016/j.foodchem.2006.11.062
  14. Djerngou, P. C., Gatsing, D., Tehuendem, M., Ngadjui, B. T., Tane, P., Ahmed, A. A., Gamal-Eldeen, A. M., Adoga, G. I., Hirata, T. and Mabry, T. J. (2006) Antitumor and immunostimulatory activity of two chromones and other constituents from Cassia petersiana. Nat. Prod. Commun. 1, 961-968
  15. Nagatsu, A., Watanabe, M., Ikemoto, K., Hashimoto, M., Murakami, N., Sakakibara, J., Tokuda, H., Nishino, H., Iwashima, A. and Yazawa, K. (1994) Synthesis and structureantitumor- promoting activity relationship of monogalactosyl diacylglycerols. Bioorg. Med. Chem. Lett. 4, 1619-1622 https://doi.org/10.1016/S0960-894X(01)80577-1