Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Quantitative Determination of Protoberebrines from the Roots of Coptis chinensis

  • Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu) ;
  • Cho, Jae-Sue (Faculty of Food Science and Biotechnology, Pukyoung National University)
  • Published : 2008.03.31
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Abstract

A simple reversed phase HPLC method was developed for extracting pharmacologically active compounds coptisine, palmatine, berberine, and epiberberine from the roots of Coptis chinensis using a binary gradient of acetonitrile : 10 mM hexanesulfonic acid-Na monohydrate with UV detection at 254 nm. The coptisine (1), palmatine (2), berberine (3), and epiberberine (4) contents of the roots of C. chinensis collected from sixteen district markets in Korea and China were $6.79\;{\sim}\;24.63\;{\mu}g/g$, $5.40\;{\sim}\;20.75\;{\mu}g/g$, $21.40\;{\sim}\;81.21\;{\mu}g/g$, and $3.45\;{\sim}\;12.04\;{\mu}g/g$, respectively.

Keywords

References

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