Outcome of Patients Undergoing Kasai Procedure for Biliary Atresia: a Study of Those Surviving More Than 10 Years with Their Native Livers

선천성 담도폐쇄증으로 Kasai 수술 후 장기 치료성적(10년 이상 생존자 대상으로)

  • Yim, Byung-Hun (Department of Surgery, St. Mary Hospital, The Catholic University of Korea) ;
  • Song, Young-Tack (Department of Surgery, St. Mary Hospital, The Catholic University of Korea) ;
  • Chung, Jae-Hee (Department of Surgery, St. Mary Hospital, The Catholic University of Korea)
  • 임병훈 (가톨릭 대학교 의과대학 외과학교실) ;
  • 송영택 (가톨릭 대학교 의과대학 외과학교실) ;
  • 정재희 (가톨릭 대학교 의과대학 외과학교실)
  • Received : 2008.10.16
  • Accepted : 2008.12.26
  • Published : 2008.12.31

Abstract

To evaluate the long-term prognosis of biliary atresia after Kasai operation, a total of 14 patients (of the 41 patients operated upon from 1982 to 1997), who had been followed up for more than 10 years, were included in this retrospective study. Eleven out of 14 patients survived with their native livers, and their data analyzed for age at operation, clearing time of jaundice, histological outcome, postoperative complications, effectiveness after the application of an intussusception anti-reflex valve, and quality of life. Average age at surgery was 62.8 days. Serum bilirubin was normalized within three months in all patients. Six among the eleven long-term survivors had ascending cholangitis as one of the postoperative complications. The application of an intussusception anti-reflux valve did not show any statistical significance in long-term survival. Most of long-term survivors appeared to enjoy good quality of life. Kasai operation might not be the definitive treatment for biliary atresia; however, Kasai operation made it possible to achieve long-term survival for patients with biliary atresia when the patients were detected and treated as early as possible.

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