The Journal of Korean Medicine (대한한의학회지)
- Volume 29 Issue 1
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- Pages.1-6
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- 2008
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- 1010-0695(pISSN)
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- 2288-3339(eISSN)
A Crossover Clinical Trial to Determine the Effect of Siguan(Four Gates) Points on Gastrointestinal Motility Suppressed by Loperamide Administration
Loperamide로 억제된 위장관 운동에 대한 사관혈의 자침효과: 무작위배정, 단일눈가림, 교차설계, 대조 임상시험
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Oh, Dal-Seok
(Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
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Jung, So-Young
(Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
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Kim, Ae-Ran
(Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
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Kang, Wee-Chang
(Dept. of Information & Statistics, Daejeon University) ;
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Park, Ji-Eun
(Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
- Koo, Chang-Mo (Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
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Choi, Jun-Yong
(Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
- Jung, Hee-Jung (Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
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Choi, Sun-Mi
(Acupuncture Moxibustion & Meridian Research Team, Department of Medical Research, Korean Institute of Oriental Medicine) ;
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Son, Chang-Gue
(East-West Cancer Center, Dunsan Hospital of Oriental Medical College, Daejeon University)
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오달석
(한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
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정소영
(한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
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김애란
(한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
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강위창
(대전대학교 통계학과) ;
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박지은
(한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
- 구창모 (한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
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최준용
(한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
- 정희정 (한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
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최선미
(한국한의학연구원 의료연구부 침구경락연구거점기반구축사업팀) ;
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손창규
(대전대학교 둔산한방병원 동서암센터)
- Published : 2008.03.31
Abstract
Objective : To investigate the therapeutic effect of manual acupuncture at Siguan (four gates, bilateral LI4 and LR3) on suppression of gastrointestinal motility. Methods : A single blind, randomized, sham-acupuncture controlled, crossover study was conducted. Twenty healthy male subjects were admitted at hospital, and gastrointestinal motility suppression was induced by loperamide administration. Just after intake of 20 radio-markers, four gates or sham acupoint treatments were administered every 12 hours, 4 times over 48 hours. Gastrointestinal motility was evaluated by radiographic distribution of the radiomarkers at stomach or ileum, ascending, transverse, descending colon, sigmoid/rectum, and outside body at serial time points (0, 6, 12, 24, and 48 h). Results : Four gates acupuncture activated gastrointestinal movement as evidenced by significantly changed distributionof radio-makers at 6, 12, and 48 hours (P < 0.0001, P = 0.001, and P = 0.03, respectively) in Cochran-Mantel-Haenszel statistics. No serious adverse events occurred in either group. Conclusions : This study showed a scientific clinical relevance of four gates acupuncture to gastrointestinal disorders.