Korean Journal of Fisheries and Aquatic Sciences (한국수산과학회지)

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
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Effect of the Green Seaweed Capsosiphon fulvescens Extract on the Liver Tissue and Fecal Cholesterol Content in Rats

매생이 추출물이 흰주의 간장조직과 분변 중의 콜레스테롤 함량에 미치는 영향

  • Jung, Eun-Jin (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Kim, In-Hye (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Hwang, Hye-Jung (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Nam, Taek-Jeong (Faculty of Food Science and Biotechnology, Pukyong National University)
  • 정은진 (부경대학교 식품생명공학부) ;
  • 김인혜 (부경대학교 식품생명공학부) ;
  • 황혜정 (부경대학교 식품생명공학부) ;
  • 남택정 (부경대학교 식품생명공학부)
  • Published : 2008.10.31
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Abstract

We investigated the effect of a green seaweed Capsosiphon fulvescens extract (CFE) on the serum, liver tissue, and fecal cholesterol levels in rats. Male Sprague-Dawley rats (four weeks old) were given on of three diets for four weeks: basal, high cholesterol, and CFE, The total serum and liver tissue cholesterol levels in the CFE group were significantly decreased compared to those in the cholesterol group. The CFE group showed increased amounts of feces, total fecal bile acid and dietary fiber as compared to basal and cholesterol group. Hematoxylin and eosin staining revealed fat droplets in the livers of the rats in the cholesterol group; however, a decreased number of droplets was observed in the rats fed the CFE diet. Our results suggest that CFE supplementation may improve lipid metabolism, by controling serum and liver tissue cholesterol levels, and by increasing the total amounts of bile acid, dietary fiber and cholesterol excretion in feces.

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References

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