Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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The Association between Obesity Indices in Adolescence and Carotid Intima-media Thickness in Young Adults: Kangwha Study

청소년기 비만지표와 초기 성인기 경동맥 내중막 두께와의 관련성: Kangwha Study

  • Lee, Yoo-Jung (Graduate School of Public Health, Yonsei University) ;
  • Nam, Chung-Mo (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Kim, Hyeon-Chang (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Hur, Nam-Wook (Biomedical Research Group, Hanyang Brain Korea 21, Hanyang University) ;
  • Suh, Il (Department of Preventive Medicine, Yonsei University College of Medicine)
  • 이유정 (연세대학교 대학원 보건학과) ;
  • 남정모 (연세대학교 의과대학 예방의학교실) ;
  • 김현창 (연세대학교 의과대학 예방의학교실) ;
  • 허남욱 (한양대학교 BK 의생명과학사업단) ;
  • 서일 (연세대학교 의과대학 예방의학교실)
  • Published : 2008.03.31
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Abstract

Objectives : The aim of this study is to investigate the association between obesity indices(body mass index, weight, waist-hip ratio and waist circumference) in adolescents and the carotid intima-media thickness (C-IMT) in early adulthood. We also wanted to identify the best predictor for C-IMT among these obesity indices. Methods : This study used community-based prospective cohort study, known as the Kangwha Study, and the data we used were from subjects who were 16-years old in 1996 (defined as "adolescence") and 25 years-old in 2005 (defined as "early adulthood"). The 256 subjects (113 men and 143 women) who were used for analysis participated in both follow-ups, and they underwent B-mode ultrasonography of the carotid arteries at the early adulthood follow-up. Obesity indices were defined as the body mass index, weight, waist-hip ratio and waist circumference. The C-IMT was defined as the mean of the maximal IMT of each common carotid artery. The C-IMT and obesity indices associations were evaluated via multivariable regression, logistic regression and the receiver-operator characteristic curve analyses. Results : In men, all the obesity indices in adolescence were showed to have statistically significant positive association with C-IMT in early adulthood. However, no such relationship was showed in women. On multiple regression and logistic regression analysis, the waist-hip ratio showed the biggest relationship with the C-IMT among the 4 obesity indices. However, there were no statistical significant differences and no best predictor was found. For the women, the obesity incidences and C-IMT showed no relationships. Conclusions : This study suggested that obesity in adolescence was related to an increase C-IMT in healthy young Korean men.

Keywords

References

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