Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Teratological Effects of Enrofloxacin on the Embryos and Fetus During the Hatching of Chicken Eggs

병아리 태자에 대한 엔로플록사신의 최기형 독성 연구

  • Lee, Jin-Heon (Dept. of Environment Education, Kongju National University, Public Health and Environmental Institute, Korea Institute Silk River Basin Institute) ;
  • Lee, Ji-Hee (Daejeon Noeun High School) ;
  • Cho, Y-Eaun (Dept. of Biology Education, Kongju National University)
  • 이진헌 (공주대학교 사범대학 환경교육과, 보건환경연구소, 금강유역환경연구소) ;
  • 이지희 (대전노은고등학교) ;
  • 조이연 (공주대학교 사범대학 생물교육과)
  • Published : 2008.08.30
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Abstract

The purpose of this study was to investigate the teratological effects of enrofloxacin, a veterinary antibiotic, on the embryos and fetus of hatching chicken eggs. A control group and four experimental fertilized egg groups were set up. The four experimental groups were injected with 0.05 ml, 0.1 ml, 0.2 ml, and 0.3 ml enrofloxacin ($50{\mu}g/ml$) respectively. During the hatching period, the weights of total eggs, inside material(yolk and white) and embryos or fetuses, embryo growth, and teratological effects were investigated. In the experimental groups (fertilized eggs injected with 0.05 ml, 0.1 ml, 0.2 ml and 0.3 ml enrofloxacin), the weights of total eggs were decreased, but the yolk and white weights were increased by the higher amount of antibiotics. The weights of embryos (fetuses) in experimental groups were 86.1%, 78.6%, 65.6% and 61.4% of the control, respectively. Retarded growth, deformity and embryo loss were observed in experimental groups. Teratological effects such as undeveloped eyes, wings and legs, and deformed head and bill were also detected. In conclusion, we found that veterinary antibiotics, enrofloxacin have made teratological effects on the embryos and fetus of hatching eggs.

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References

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