참고문헌
- Hayflick, L. and Moorhead, P. S. (1961) The serial cultivation of human diploid cell strains. Exp. Cell Res. 25, 585-621. https://doi.org/10.1016/0014-4827(61)90192-6
- Harley, C. B., Futcher, A. B. and Greider, C. W. (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345, 458-460. https://doi.org/10.1038/345458a0
- Allsopp, R. C., Vaziri, H., Patterson, C., Goldstein, S., Younglai, E. V., Futcher, A. B., Greider, C. W. and Harley, C. B. (1992) Telomere length predicts replicative capacity of human fibroblasts. Proc. Natl. Acad. Sci. 89, 10114- 10118. https://doi.org/10.1073/pnas.89.21.10114
- d'Adda di Fagagna, F., Reaper, P. M., Clay-Farrace, L., Fiegler, H., Carr, P., Von Zglinicki, T., Saretzki, G., Carter, N. P. and Jackson, S. P. (2003) A DNA damage checkpoint response in telomere-initiated senescence. Nature 426, 194-198. https://doi.org/10.1038/nature02118
- Vaziri, H., West, M. D., Allsopp, R. C., Davison, T. S., Wu, Y. S., Arrowsmith, C. H., Poirier, G. G. and Benchimol, S. (1997) ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J. 16, 6018-6033. https://doi.org/10.1093/emboj/16.19.6018
- Campisi, J. and d'Adda di Fagagna, F. (2007) Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell. Biol. 8, 729-740 https://doi.org/10.1038/nrm2233
- Ben-Porath, I. and Weinberg, R. A. (2005) The signals and pathways activating cellular senescence. Int. J. Biochem. Cell Biol. 37, 961-976. https://doi.org/10.1016/j.biocel.2004.10.013
- Campisi, J. (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120, 513-522. https://doi.org/10.1016/j.cell.2005.02.003
- Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I. and Pereira-Smith, O. (1995) A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. USA 92, 9363-9367. https://doi.org/10.1073/pnas.92.20.9363
- Narita, M., Nunez, S., Heard, E., Narita, M., Lin, A. W., Hearn, S. A., Spector, D. L., Hannon, G. J. and Lowe, S. W. (2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113, 703-716. https://doi.org/10.1016/S0092-8674(03)00401-X
- Funayama, R. and Ishikawa, F. (2007) Cellular senescence and chromatin structure. Chromosoma. 116, 431-440. https://doi.org/10.1007/s00412-007-0115-7
- Seong, Y. S., Min, C., Li, L., Yang, J. Y., Kim, S. Y., Cao, X., Kim, K., Yuspa, S. H., Chung, H. H. and Lee, K. S. (2003) Characterization of a novel cyclin-dependent kinase 1 inhibitor, BMI-1026. Cancer Res. 63, 7384-7391.
- Collins, I. and Garrett, M. D. (2005) Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors. Curr. Opin. Pharmacol. 5, 366-373. https://doi.org/10.1016/j.coph.2005.04.009
- Park, W. Y., Park, J. S., Cho, K. A., Kim, D. I., Ko, Y. G., Seo, J. S. and Park, S.C. (2000) Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells. J. Biol. Chem. 275, 20847-20852. https://doi.org/10.1074/jbc.M908162199
- Cho, K. A., Ryu, S. J., Park, J. S., Jang, I. S., Ahn, J. S., Kim, K. T. and Park, S. C. (2003) Senescent phenotype can be reversed by reduction of caveolin status. J. Biol. Chem. 278, 27789-27795. https://doi.org/10.1074/jbc.M208105200
- Park, S. C., Yeo, E. J., Han, J. A., Hwang, Y. C., Choi, J. Y., Park, J. S., Park, Y. H., Kim, K. O., Kim, I. G., Seong, S.C. and Kwak, S. J. (1999) Aging process is accompanied by increase of transglutaminase C. J. Gerontol. A Biol. Sci. Med. Sci. 54, B78-83. https://doi.org/10.1093/gerona/54.2.B78
- Serrano, M., Lim, A. W., McCurrach, M. E., Beach, D. and Lowe, S.W. (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK1A. Cell 88, 593-602. https://doi.org/10.1016/S0092-8674(00)81902-9
- Lin, A. W., Barradas, M., Stone, J. C., van Aelst, L., Serrano, M. and Lowe, S. W. (1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes. Dev. 12, 3008-3019. https://doi.org/10.1101/gad.12.19.3008
- Zhu, J. Y., Woods, D., McMahon, M. and Bishop, J. M. (1998) Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev. 12, 2997-3007. https://doi.org/10.1101/gad.12.19.2997
- Takada, Y., Sethi, G., Sung, B. and Aggarwal, B. B. (2008) Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells. Mol. Pharmacol. 73, 1549-1557. https://doi.org/10.1124/mol.107.041350
- Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J. Stradley, D. A. Feeser, W. S., Van Dyk, D. E., Pitts, W. J., Earl, R. A., Hobbs, F., Copeland, R. A., Magolda, R. L., Scherle, P. A. and Trzaskos, J. M. (1998) Identification of a novel mitogen inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273, 18623-18632. https://doi.org/10.1074/jbc.273.29.18623
- Robinson, M. J. and Cobb, M. H. (1997) Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 9, 180-186. https://doi.org/10.1016/S0955-0674(97)80061-0
- Kim-Kaneyama, J. R., Nose, K. and Shibanuma, M. (2000) Significance of nuclear relocalization of ERK1/2 in reactivation of c-fos transcription and DNA synthesis in senescent fibroblasts. J. Biol. Chem. 275, 20685-20692. https://doi.org/10.1074/jbc.M908723199
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