참고문헌
- Ferrara JL, Reddy P. Pathophysiology of graft-versus-host disease. Semin Hematol 2006;43:3-10 https://doi.org/10.1053/j.seminhematol.2005.09.001
- Teshima T, Ferrara JL. Pathogenesis and prevention of graft-versus-host disease. Curr Opin Organ Transplant 2001; 6:265-71 https://doi.org/10.1097/00075200-200109000-00012
- Martin PJ, Hansen JA, Buckner CD, Sanders JE, Deeg HJ, Stewart P, et al. Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts. Blood 1985;66:664-72
- Horowitz MM, Gale RP, Sondel PM, Goldman JM, Kersey J, Kolb HJ, et al. Graft-versus-leukemia reactions after bone marrow transplantation. Blood 1990;75:555-62
- Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-64
- Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immuno. 2003;3:199-210 https://doi.org/10.1038/nri1027
-
Trenado A, Charlotte F, Fisson S, Yagello M, Klatzmann D, Salomon BL, et al. Recipient-type specific
$CD4^+CD25^+$ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versusleukemia. J Clin Invest 2003;112:1688-96 https://doi.org/10.1172/JCI17702 -
Jones SC, Murphy GF, Korngold R. Post-hematopoietic cell transplantation control of graft-versus-host disease by donor
$CD4^+CD25^+$ T cells to allow an effective graft-versusleukemia response. Biol Blood Marrow Transplant 2003;9: 243-56 https://doi.org/10.1053/bbmt.2003.50027 -
Sakaguchi S, Sakaguchi N, Shimizu J, Yamazaki S, Sakihama T, Itoh M, et al. Immunologic tolerance maintained by
$CD4^+CD25^+$ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001;182:18-32 https://doi.org/10.1034/j.1600-065X.2001.1820102.x -
Hoffmann P, Ermann J, Edinger M, Fathman CG, Strober S. Donor-type
$CD4^+CD25^+$ regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation J Exp Med 2002;196:389-99 https://doi.org/10.1084/jem.20020399 -
Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL.
$CD4^+CD25^+$ immunoregulatory T cells: new therapeutics for graft-versus-host disease. J Exp Med 2002;196:401-6 https://doi.org/10.1084/jem.20020090 -
Taylor PA, Lees CJ, Blazar BR. The infusion of ex vivo activated and expanded
$CD4^+CD25^+$ immune regulatory cells inhibits graft-versus-host disease lethality. Blood 2002;99: 3493-9 https://doi.org/10.1182/blood.V99.10.3493 - Glucksberg H, Storb R, Fefer A, Buckner CD, Neiman PE, Clift RA, et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA-matched sibling donors. Transplantation 1974;18:295-304 https://doi.org/10.1097/00007890-197410000-00001
-
Hanash AM, Levy RB. Donor
$CD4^+CD25^+$ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation. Blood 2005;105:1828-36 https://doi.org/10.1182/blood-2004-08-3213 -
Baecher-Allan C, Brown JA, Freeman GJ, Hafler DA.
$CD4^+$ CD25high Regulatory cells in human peripheral blood. J Immunol 2001;167:1245-53 https://doi.org/10.4049/jimmunol.167.3.1245 - Stanzani M, Martins SL, Saliba RM, St John LS, Bryan S, Couriel D, et al. CD25 expression on donor CD4 or CD8 T cells is associated with an increased risk for graft-versushost disease after HLA-identical stem cell transplantation in humans. Blood 2004;103:1140-6 https://doi.org/10.1182/blood-2003-06-2085
-
Clark FJ, Gregg R, Piper K, Dunnion D, Freeman L, Griffiths M, et al. Chronic graft-versus-host disease is associated with increased numbers of peripheral blood
$CD4^+$ CD25 high regulatory T cells. Blood 2004;103:2410-6 https://doi.org/10.1182/blood-2003-06-2073 -
Sanchez J, Casano J, Alvarez MA, Roman-Gomez J, Martin C, Martinez F, Gomez P, et al. Kinetic of regulatory CD25high and activated
$CD134^+$ (OX40) T lymphocytes during acute and chronic graft-versus-host disease after allogeneic bone marrow transplantation. Br J Haematol 2004;126:697-703 https://doi.org/10.1111/j.1365-2141.2004.05108.x - Miura Y, Thoburn CJ, Bright EC, Phelps ML, Shin T, Matsui WH, et al. Association of Foxp3 regulatory gene expression with graft-versus-host disease. Blood 2004;104: 2187-93 https://doi.org/10.1182/blood-2004-03-1040
-
Zorn E, Kim HT, Lee SJ, Floyd BH, Lista D, Arumugarajah S, et al. Reduced frequency of FOXP3+
$CD4^+CD25^+$ regulatory T cells in patients with chronic graft-versus-host disease. Blood 2005;106:2903-11 https://doi.org/10.1182/blood-2005-03-1257 - Auletta JJ, Lazarus HM. Immune restoration following hematopoietic stem cell transplantation: an evolving target. Bone Marrow Transplant 2005;35:835-57 https://doi.org/10.1038/sj.bmt.1704966
- Storek J, Witherspoon RP. Immunological reconstitution after hematopoietic stem cell transplantation. In: Atkinson K, Champlin R, Ritz J, Fibbe WE, Ljungman P, Brenner MK. Clinical bone marrow and blood stem cell transplantation, 3rd ed. Cambridge: Cambridge University Press, 2004:194-226