Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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A case of herpes zoster in a 4-month-old infant

4개월 영아에서 발생한 대상포진 1예

  • Kim, Ji Hyun (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Lee, Jung Ju (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Yun, Sin Weon (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Chae, Soo Ahn (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Lim, In Seok (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Lee, Dong Keun (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Choi, Eung Sang (Department of Pediatrics, College of Medicine, Chung-Ang University) ;
  • Yoo, Byoung Hoon (Department of Pediatrics, College of Medicine, Chung-Ang University)
  • 김지현 (중앙대학교 의과대학 소아과학교실) ;
  • 이정주 (중앙대학교 의과대학 소아과학교실) ;
  • 윤신원 (중앙대학교 의과대학 소아과학교실) ;
  • 채수안 (중앙대학교 의과대학 소아과학교실) ;
  • 임인석 (중앙대학교 의과대학 소아과학교실) ;
  • 이동근 (중앙대학교 의과대학 소아과학교실) ;
  • 최응상 (중앙대학교 의과대학 소아과학교실) ;
  • 유병훈 (중앙대학교 의과대학 소아과학교실)
  • Received : 2008.08.17
  • Accepted : 2008.10.17
  • Published : 2008.12.15
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Abstract

Herpes zoster in infancy is very rare but can be developed following intrauterine or postnatal exposure to varicella zoster virus. We report a case of herpes zoster in a 4-month-old male infant. He had no prior history of primary varicella or varicella vaccination. His mother had no history of varicella infection and no contact history with varicella during pregnancy. He had a history of exposure to his father with herpes zoster 3 months ago, and to his cousin with convalescent chickenpox 2 months ago. Multinucleated, giant cells were shown on a Tzanck smear. He was treated with acyclovir and first generation cephalosporin for herpes zoster with Staphylococcal skin infection, with complete resolution without sequelae.

영아에서의 대상포진은 매우 드문 질환이지만, 자궁 내에서 혹은 출생 후 수두 바이러스에 노출되어 발생할 수 있다. 태생기에는 바이러스에 대한 특이 면역글로불린 수치가 낮으며, 영아기에는 항원에 반응하는 림프구, 자연살해세포, 사이토카인이 적어 바이러스의 잠복기를 유지하기가 어려워, 이 때에 감염되는 경우 생후 1년 이내에 대상포진이 발병하는 것으로 알려져 있다. 저자들은 수두에 이환 되었거나 수두 예방접종을 받았던 적이 없었던 생후 4개월 영아에서 대상포진을 경험하였기에 보고하는 바이다. 환아의 어머니 역시 임신 중 수두에 감염되었거나 노출된 병력이 없었으며 환아는 대상포진에 병발된 포도상구균 감염에 대하여 acyclovir와 1세대 세팔로스포린으로 치료를 받고, 합병증 없이 치료되었다.

Keywords

References

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