수출입 식물검역업체 근로자의 공기 중 Methyl Bromide 노출에 관한 연구

Workers' Exposure to Airborne Methyl Bromide in the Exporting/Importing Plants and Products Quarantine Company

  • 이현석 (인제대학교 보건안전공학과) ;
  • 신용철 (인제대학교 보건안전공학과)
  • Lee, Hyun Seok (Department of Occupational Health and Safety Engineering, Inje University) ;
  • Shin, Yong Chul (Department of Occupational Health and Safety Engineering, Inje University)
  • 투고 : 2007.11.16
  • 심사 : 2008.03.17
  • 발행 : 2008.03.31

초록

Methyl bromide has been used as a representative fumigant for quarantine, and several poisoning cases have occurred recently by this chemical in Korea. The purpose of this study is to evaluate workers' exposures to airborne methyl bromide in the importing and exporting plant products quarantine companies. Air samples were collected 400/200 mg Anasorb 747TM and were analyzed by gas chromatograph /flame ionization detector according to the Occupational Safety and Health Agency (OSHA) Method PV2040. Geometric mean (GM) and arithmetic mean (AM) of total 27 workers' exposure concentrations to airborne methyl bromide were 1.12 ppm and 0.24 ppm, respectively. Two exposures(12.1 ppm and 12 ppm as 8hr-TWA) of total 27 workers' exposures exceeded the Korean standard (5 ppm) of Ministry Labor, while 4 exposures (15%) exceeded the Threshold Limit Value (TLV) (1 ppm) of American Conference of Governmental Industrial Hygienists (ACGIH). Seven samples (11%) of total 63 short-term air samples exceeded the OSHA Permissible Exposure Limit (PEL) 20 ppm (Ceiling). The opening (management) task in wood fumigation by tent showed the highest short-term exposure concentrations (AM: 18.6 ppm, GM: 0.58 ppm, maximum: 340.7 ppm). The maximum level in treatment task of the same process was 2.01 ppm. Methyl bromide concentrations in opening operation was significantly higher than that in treatment operation (p<0.05). In conclusion, the GM of workers' 8hr-TWA exposures to airborne methyl chloride in the importing/exporting plant quarantine industry was estimated below the ACGIH TLV (1 ppm). However, opening task in the fumigation of wood being covered with tent or fumigation of pant products in container showed the levels exceeding ACGIH TLV (1 ppm), and opening task in the fumigation of wood being covered with tent showed the level exceeding the Korean standard of Ministry of Labor (5 ppm).

키워드

참고문헌

  1. 국립식물검역소. 수출입식물검역소독처리규정-식물검역소독처리기준, 고시 제2000-6호; 2001
  2. 국립식물검역소. 수출입방제(MB 훈증)업체 현황. [Cited 2006 December 1] Available from :http://www.npqs.go.kr/ homepage/plant_info/plant_info_042.asp
  3. 노동부. 산업안전보건법 산업보건기준에 관한규칙 노동부령제195호; 2003
  4. 노동부. 보호구 성능검정 규정 (방독마스크), 고시 제2000-15호; 2000
  5. 노동부. 화학물질 및 물리적 인자의 노출기준, 고시 제97-65호; 1998
  6. 대한산업보건협회. 중독발생사례/브롬화메틸. 창고 훈증작업중 발생한 브롬화메틸 중독. 대한산업보건협회 1995
  7. 박태혁, 김정일, 손지언, 김종국, 김형수, 정갑열, 김준연. 농산물 소독과정에서 브롬화메틸에 노출된 근로자에게 발생한 신경병 2례. 대한산업의학회지, 2000; 12(4): 547-553
  8. (사)유독물관리협회. 유해물질방제요령;1992.(114쪽.)
  9. 조광덕, 송선홍, 이난영, 최은진, 임수빈, 이순금, 김광국. 급성 methyl bromide 중독 환자에서 보인 전기생리학적 이상소견. 대한신경과학회지 2005;23(1):138-141
  10. 조광덕, 임수빈, 이순금, 최성훈, 김태훈, 한군희, 송경일. 발작과 의식저하를 동반한 급성 methyl bromide 중독 2예. 대한간질학회지 2003;7(2):125-129
  11. 외무부 국제경제국. 몬트리올 의정서 제9차 당사국총회 결과보고서(1997. 9.9-17, 캐나다 몬트리올). 행정간행물등록번호 17000-25281-57-9753: 1997
  12. 이경우. 훈증방제에 관한연구. 휴미캡, 1998
  13. 이종성, 이용학, 신재훈, 최정근, 오차재, 정호근. 방역작업자의 브롬화메틸 노출수준과 생물학적 모니터링. 한국산업위생학회지 2001;11(3):212-218
  14. 조숙자, 이광용, 정지연, 김성진, 박정선, 정호근. 수출입식물 훈증작업에서 근로자의 메틸브로마이드 노출평가(I). 작업관련 건강유해도평가보고서. DHHR-RHE-01-06. 한국산업안전공단 산업안전보건연구원, 2001
  15. 정규철. 산업중독학편람. 신광출판사, 1995.(584-587쪽.)
  16. 최광동, 신진홍, 김대성, 정대수, 박규현, 오차재, 조병만, 조차재. 만성 메틸브로마이드 중독에 의한 다발성 신경장애. 대한신경과학회지 2002;20(3):307-310
  17. 한국작물보호협회. 농약사용지침서-영일케미컬.[Cited 2006 December 1] Available from :http://koreacpa.org/index3/ guide/up_file/guide/5702368.PDF
  18. American Conference of Governmental Industrial Hygienists(ACGIH). 2005 TLVs and BEIs. ACGIH, 2004
  19. ACGIH, Documentation of the TLVs$circledR$ and BEIs$circledR$ with other Worldwide Occupational Exposure Values. CD-ROM 2005, ACGIH, Cincinnati, OH, 2005
  20. Bauer JD. Clinical laboratory methods 9th ed; clinical chemistry. C.V. Mosby; 1982
  21. California Environmental Protection Agency. Review of Restriction on the Use of Methyl Bromide. Sacramento, California, California EPA DPR; November 1996
  22. Garrier, R Rambourg-Schepense MO, Mullerr A, Hallier E. Glutathion transferase activity and formation of macromolecular adducts in twe cases of acute methyl bromide poisoning, Occup. Environ. Med. 1996; 53: 211-215 https://doi.org/10.1136/oem.53.3.211
  23. Herzstein, J. and Mark R. Cullen. Methyl Bromide Intoxication in Four Field-Workers During Removal of Soil Fumigation Sheets. American Journal of Industrial Medicine, 1990; 17: 321-326 https://doi.org/10.1002/ajim.4700170304
  24. Hornung, R.W. and L.D. Reed: Estimation of average concentration in the presence of nondetectable values. Appt. Occup. Env. Hyg. 1990; 5: 46-51 https://doi.org/10.1080/1047322X.1990.10389587
  25. LaDou J ed. Occupational & Environmental Medicine. 2nd Edition. 1997. Stamford: Appleton and Lange. P. 531-570
  26. OSHA(Occupational Safety and Health Agency). Sample and Analytical Methods
  27. [Cited 2006 September 1] Available from : http://www.osha.gov/dts/ sltc/methods/partial/pv2040/2040.html
  28. NIOSH.(National Institute for Occupational Safety and Health, 1994) Documentation for Immediately Dangerous to Life or Health Concentration.[Cited 2006 October 1]; Available from: http: //www.cdc.gov/niosh/idlh/idlhintr.html
  29. NIOSH. Methyl Bromide(updated 1996).[Cited 2006 October 1]; Available from : http: //www.cdc.gov/niosh/idlh/74839.html
  30. NIOSH. MONOHALOMETHANES. Cincinnati, DHHS (NIOSH) Pub. No. 84-117; September 27, 1984
  31. Tanaka S, Abuku S, Seki Y, Imamiya S. Evaluation of methyl bromide exposure on the plant quarantine fumigators by envirnmental and biological monitoring. Ind Health 1991; 29(1) :11-21 https://doi.org/10.2486/indhealth.29.11
  32. Torkelson, T.R. and V.K. Rowe. Methyl bromide. In: Clayton GD, Clayton FE, eds. Patty's Industrial Hygiene and Toxicology, 3rd ed., New York: John Wiley and Sons, 1981. P. 3442-3446
  33. U.S EPA. Methyl Bromide Phase Out Web Site.(Cited 2006 December 12): Available from : http://www.epa.gov/ozone/mbr
  34. U.S. National Toxicology Program: Toxicology and Carcinogenesis Studies of methyl bromide (CAS No. 74-83-9) In B6C3F1 Mice (Inhalation Studies). NTP Technical Report Series No. 385, DHHS (NIH) Pub. No.92-2840. U.S. National Institutes of Health, NTP, Research Triangle Park, NC, 1992
  35. Van den oever, R., D. Roosels, and D. Lahaye. Actual hazard of methyl bromide fumigation in soil disinfection. British Journal of Industrial Medicine, 1982; 39: 140-144
  36. Yamamoto O, Hori H, Tanaka I, Asahi M, Koga M. : Experimental exposure of rat skin to methyl bromide: a toxicokinetic and histopathological study. Arch Toxicol. 2000 Feb; 73(12): 641-648 https://doi.org/10.1007/s002040050019