Annals of Hepato-Biliary-Pancreatic Surgery (한국간담췌외과학회지)
- Volume 12 Issue 4
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- Pages.302-306
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- 2008
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- 2508-5778(pISSN)
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- 2508-5859(eISSN)
A Case of Surgical Treatment of Nesidioblastosis with Hyperinsulinemic Hypoglycemia in an Adult
국소형 췌소도세포증(Nesidioblastosis) 1예
- Kang, Bong-Su (Department of Surgery, College of Medicine Pochon CHA University) ;
- Kang, Sung-Il (Department of Surgery, College of Medicine Pochon CHA University) ;
- Koo, Hye-Young (Department of Surgery, College of Medicine Pochon CHA University) ;
- Lee, Sung-Bae (Department of Surgery, College of Medicine Pochon CHA University) ;
- Kang, Hye-Yun (Department of Pathology, College of Medicine Pochon CHA University) ;
- Park, Seok-Won (Department of Endocrinology, College of Medicine Pochon CHA University) ;
- Chung, Chul-Woon (Department of Surgery, College of Medicine Pochon CHA University)
- 강봉수 (포천중문대학교 의과대학 외과학교실) ;
- 강성일 (포천중문대학교 의과대학 외과학교실) ;
- 구혜영 (포천중문대학교 의과대학 외과학교실) ;
- 이성배 (포천중문대학교 의과대학 외과학교실) ;
- 강혜윤 (포천중문대학교 의과대학 병리학교실) ;
- 박석원 (포천중문대학교 의과대학 내과학교실) ;
- 정철운 (포천중문대학교 의과대학 외과학교실)
- Published : 2008.12.30
Abstract
Nesidioblastosis is a rare disorder, and it usually considered as a cause of neonatal hyperinsulinemic hypoglycemia. A 35 year-old-woman with hyperinsulinemic hypoglycemia was admitted in an unconscious condition. Abdominal CT, pancreas MRI and celiac angiography with an intra-arterial calcium stimulation test revealed a suspicious insulin-producing tumorous lesion in the head of pancreas. The patient underwent enucleation of the pancreas head tumor under the initial diagnosis of insulinoma. However, the tumor was confirmed histologically as nesidioblastosis that showed ductoendocrine proliferations and numerous small endocrine cell groups. Nesidioblastosis is classified into a focal type and a diffuse type, which are characterized by different clinical outcomes. The patient in our case showed a normal blood glucose level after operation, which is often the case for the focal type. Herein, we report this very rare case of adult nesiodioblastosis that was successfully treated by surgical resection.