Korean Journal of Acupuncture
- 제25권3호
- /
- Pages.97-115
- /
- 2008
- /
- 2287-3368(pISSN)
- /
- 2287-3376(eISSN)
음곡 육종용 약침이 난소적출 생쥐의 골다공증에 미치는 영향
Effects of Herbal-Acupuncture with Cistanches Herba Extract at KI10 (Eumgok) on Osteoporosis in Ovariectomized Mice
- 정년식 (대전대학교 한의과대학 경락경혈학교실) ;
- 이병렬 (대전대학교 한의과대학 침구학교실) ;
- 구성태 (부산대학교 한의학전문대학원 경락구조의학부) ;
- 임윤경 (대전대학교 한의과대학 경락경혈학교실)
- Jeung, Neon-Sik (Dept. of Meridian & Acupoint, College of Oriental Medicine, Deajeon University) ;
- Lee, Byung-Ryul (Dept. of Acupuncture & Moxibution, College of Oriental Medicine, Deajeon University) ;
- Koo, Sung-Tae (Division of Meridian and Structural Medicine, School of Oriental Medicine, Pusan National University) ;
- Yim, Yun-Kyoung (Dept. of Meridian & Acupoint, College of Oriental Medicine, Deajeon University)
- 발행 : 2008.09.27
초록
Objective & Methods : This study aimed to evaluate the effects of Cistanches Herba herbal-acupuncture (CH-HA) at KI10 (Umgok) on osteoporosis induced by ovariectomy in mice. The results were as follows; Results : CH-HA at KI10 significantly inhibited the overgrowth of tibia, the elevation of serum osteocalcin level, the reduction of tibial Ca and P level, the increase of tibial osteoclast like cells, the reduction of tibial TBV (trabecular bone volume), the overgrowth of tibial GPL (growth plate length) in ovariectomized mice. NP at KI10 significantly inhibited the reduction of BMD (bone mineral density) in ovariectomized mice, but CH-HA did not. Conclusion : Taken together, CH-HA at KI10 has a protective or therapeutic effect for osteoporosis in ovariectomized mice. Therefore, it is suggested that CH-HA may be an useful therapeutics in clinical filed after further researches.