Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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A Case of Colchicine Intoxication Presenting as Acute Gastroenteritis

위장관염으로 오인된 콜히친 중독 1례

  • Ahn, Ji-Yun (Department of Emergency Medicine, College of Medicine, Hallym University) ;
  • Sohn, You-Dong (Department of Emergency Medicine, College of Medicine, Hallym University) ;
  • Kwon, Hyuk-Sool (Department of Emergency Medicine, College of Medicine, Hallym University) ;
  • Ahn, Hee-Chol (Department of Emergency Medicine, College of Medicine, Hallym University)
  • 안지윤 (한림대학교 의과대학 응급의학교실) ;
  • 손유동 (한림대학교 의과대학 응급의학교실) ;
  • 권혁술 (한림대학교 의과대학 응급의학교실) ;
  • 안희철 (한림대학교 의과대학 응급의학교실)
  • Published : 2008.12.31
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Abstract

A 47-year-old woman ingested about 12 mg of colchicine with suicidal intent. Colchicine, a highly poisonous alkaloid, is a commonly used treatment for gout, Bechet's disease, and familial Mediterranean fever. Despite the knowledge of its side effects, the risk of a significant overdose is under-appreciated. She suffered from acute multisystem toxicity, including gastrointestinal disorders, bone marrow suppression, alopecia, and probable pancreatitis, but she ultimately recovered with supportive therapy. We report a case of acute colchicine toxicity from a single overdose with a review of the literature.

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