The Korea Journal of Herbology (대한본초학회지)
- Volume 23 Issue 4
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- Pages.113-120
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- 2008
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Anti-atherosclerosis Effect of Imyosan Extract in Human Aortic Smooth Muscle Cells
사람 대동맥 평활근 세포에서 이묘산(二妙散)의 항동맥경화 활성
- Yun, Hyun-Jeong (Cardiovascular Medical Research Center, College of Oriental Medicine, Dongguk University) ;
- Heo, Sook-Kyoung (Cardiovascular Medical Research Center, College of Oriental Medicine, Dongguk University) ;
- Yi, Hyo-Seung (Cardiovascular Medical Research Center, College of Oriental Medicine, Dongguk University) ;
- Kim, Tae-Hoon (Department of Prescriptionology, Collage of Oriental Medicine, Dongguk University) ;
- Kim, Dong-Wan (Department of Prescriptionology, Collage of Oriental Medicine, Dongguk University) ;
- Kim, Sun-Mo (Department of Prescriptionology, Collage of Oriental Medicine, Dongguk University) ;
- Park, Sun-Dong (Cardiovascular Medical Research Center, College of Oriental Medicine, Dongguk University)
- 윤현정 (동국대학교 한의과대학 심혈관계질환 천연물 연구개발센터) ;
- 허숙경 (동국대학교 한의과대학 심혈관계질환 천연물 연구개발센터) ;
- 이효승 (동국대학교 한의과대학 심혈관계질환 천연물 연구개발센터) ;
- 김태훈 (동국대학교 한의과대학 방제학교실) ;
- 김동완 (동국대학교 한의과대학 방제학교실) ;
- 김선모 (동국대학교 한의과대학 방제학교실) ;
- 박선동 (동국대학교 한의과대학 심혈관계질환 천연물 연구개발센터)
- Published : 2008.12.30
Abstract
Objectives: This study was evaluated to elucidate the inhibitory potential of Imyosan(IMS) and its components, Phellodendri Cortex(PC: Phellodendron amurense Rupr., Hwangbaek in Korean) and Atractylodis Rhizoma(AR: Atratylodes lancea D.C., Changchool in Korean), on human aortic smooth muscle cells(HASMC) migration and production of matrix metalloproteinase (MMP)-2 and MMP-9 by TNF-
Keywords
- Imyosan(IMS);
- Phellodendri Cortex(PC);
- Atractylodis Rhizoma(AR);
- migration;
- matrix metalloproteinase(MMP)