Preparation of Morpholine-2-one and 1,4-Oxazepan-2-one Derivatives by Cyclization Reaction between N-Bts Amino Alcohol and Chloroacetyl Chloride

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Greene, T. W.; Wuts, P. G. M. Protective Groups in Organic Synthesis, 4th Ed., John Wiley & Sons, Inc.: 2007
Vedejs, E.; Lin, S.; Klapars, A.; Wang, J. J. Am. Chem. Soc. 1996, 118, 9796 https://doi.org/10.1021/ja961485n
Vedejs, E.; Kongkittingam, C. J. Org. Chem. 2000, 65, 2309 https://doi.org/10.1021/jo9914115
Caldwell, W. T.; Kornfeld, E. C. J. Am. Chem. Soc. 1942, 64, 1695 https://doi.org/10.1021/ja01259a063
Roblin, R. O.; Clapp, J. W. J. Am. Chem. Soc. 1950, 72, 4890 https://doi.org/10.1021/ja01167a011
Stephen, W. W.; Kelly, N. H. J. Org. Chem. 2006, 71, 1080 https://doi.org/10.1021/jo052164+
Lee, H.; Jeon, J. H.; Lim, C. J.; Choi, H.; Yoon, Y.; Kim, S. K. Org. Lett. 2007, 9, 3291 https://doi.org/10.1021/ol071215h
Gerhard, S.; Glynn, M. J. Agric. Food Chem. 2001, 49, 138 https://doi.org/10.1021/jf0010432
Ku, I. W.; Cho, S.; Doddareddy, M. R.; Jang, M. S.; Keum, G.; Lee, J. H.; Chung, B. Y.; Kim, Y.; Rhima, H.; Kanga, S. B. Bioorg. Med. Chem. Lett. 2006, 16, 5244 https://doi.org/10.1016/j.bmcl.2006.05.031
Naveenkumar, K.; Chandrashekar, R. E.; Muthulingam, A.; Srinivas, G.; Pravinchandra, J. V.; Yerremilli, A.; Apurba, B.; Sundaram, V.; Vijayavitthal, T. M. Org. Process Res. Dev. 2007, 11, 455 https://doi.org/10.1021/op700030d

In silico investigation of morpholines as novel class of trypanosomal triosephosphate isomerase inhibitors vol.26, pp.1, 2017, https://doi.org/10.1007/s00044-016-1739-z
ChemInform Abstract: Preparation of Morpholine-2-one and 1,4-Oxazepan-2-one Derivatives by Cyclization Reaction Between N-Bts Amino Alcohol and Chloroacetyl Chloride. vol.40, pp.2, 2009, https://doi.org/10.1002/chin.200902166