Bulletin of the Korean Chemical Society

  • 제29권10호
  • /
  • Pages.1887-1892
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  • 2008
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Synthesis and Characterization of Novel Amino Acid-conjugated Poly(aspartic acid) Derivatives

  • 발행 : 2008.10.20
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초록

Novel poly(aspartic acid) derivatives conjugated with L-lysine moieties and their amphiphilic analogs were synthesized and characterized. The chemical structures of these polymers were confirmed using FT-IR and $^1HNMR$ spectroscopy. The physicochemical properties of amphiphilic copolymers were characterized using an electrophonetic light scattering spectrophotometer (ELS) and transmission electron microscopy (TEM). These results indicated a stable nanoparticle formation within aqueous media. These polymers have potential applications in the pharmaceutical and cosmetic fields as delivery vehicles for bioactive molecules.

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참고문헌

  1. Min, S. K.; Kim, S. H.; Kim, J. H. Journal of Industrial Engineering Chemistry 2000, 6(4), 276
  2. Giammona, G.; Pitarresi, G.; Tomarchio, V.; Spadaro, G. Colloid and Polymer Science 1995, 273(6), 559 https://doi.org/10.1007/BF00658685
  3. Nacato, T.; Yoshitake, M.; Matsubara, K.; Tomida, M.; Kakuchi, T. Macromolecules 1998, 31(7), 2107 https://doi.org/10.1021/ma971629y
  4. Wheeler, A. P.; Kosan, L. P. Mat. Res. Soc. Symp. Proc. 1993, 292, 279
  5. Nakato, T.; Kusuno, A.; Kakuchi, A. J. Polym. Sci., Polym. Chem. 2000, 38(1), 117 https://doi.org/10.1002/(SICI)1099-0518(20000101)38:1<117::AID-POLA15>3.0.CO;2-F
  6. Masubara, K.; Nakato, T.; Tomida, M. Macromolecules 1997, 30(8), 2305 https://doi.org/10.1021/ma961579h
  7. Kang, H. S.; Shin, M. S.; Kim, J. D.; Yang, J. W. Polymer Bulletin 2000, 45, 39 https://doi.org/10.1007/s002890070054
  8. Kang, H. S.; Yang, S. R.; Kim, J. D.; Han, S. H.; Chang, I. S. Langmuir 2001, 17, 7501 https://doi.org/10.1021/la0107953
  9. Jiang, T. Y.; Wang, Z. Y.; Tang, L. X.; Mo, F. K.; Chen, C. Journal of Applied Polymer Science 2006, 99, 2702 https://doi.org/10.1002/app.22818
  10. Jiang, T. Y.; Wang, Z. Y.; Chen, C.; Mo, F. K.; Xu, Y. L.; Tang, L. X.; Liang, J. J. Journal of Applied Polymer Science 2006, 101, 2871 https://doi.org/10.1002/app.23353
  11. Bach, Q. V.; Moon, J.-R.; Lee, D. S.; Kim, J.-H. Journal of Applied Polymer Science 2008, 107(1), 509 https://doi.org/10.1002/app.27138
  12. Horgan, A.; Saunderd, B.; Vincent, B.; Heenan, R. K. J. Colloid Interf. Sci. 2003, 262, 548 https://doi.org/10.1016/S0021-9797(03)00239-X
  13. Zhu, G. Eur. Polym. J. 2005, 41, 2671 https://doi.org/10.1016/j.eurpolymj.2005.05.023
  14. Li1, P.; Yin, Y. L.; Li, D.; Kim, S. W.; Wu, G. British Journal of Nutrition 2007, 98, 237 https://doi.org/10.1017/S000711450769936X
  15. Jeong, J. H.; Park, T. G. Journal of Controlled Release 2002, 82, 159 https://doi.org/10.1016/S0168-3659(02)00131-1
  16. Goddard, J. M.; Hotchkiss, J. H. Prog. Polym. Sci. 2007, 32, 3698
  17. Yang, S. R.; Lee, H. J.; Kim, J. D. Journal of Controlled Release 2006, 114, 60 https://doi.org/10.1016/j.jconrel.2006.05.016
  18. Qingling, X.; Lingling, A.; Minghui, Y.; Shu, W. Macromol. Rapid Communication 2008, 29, 390 https://doi.org/10.1002/marc.200700745
  19. Moon, J. R.; Kim, B. S.; Kim, J. H. Bull. Korean Chem. Soc. 2006, 27, 981 https://doi.org/10.5012/bkcs.2006.27.7.981
  20. Stella, B.; Arpicco, S.; Peracchia, M. T.; Desmaele, D.; Hoebeke, J.; Renoir, M.; Dangelo, J.; Cattel, L.; Couvreur, P. Journal of Pharmaceutical Sciences 2000, 89(11), 1452 https://doi.org/10.1002/1520-6017(200011)89:11<1452::AID-JPS8>3.0.CO;2-P
  21. Stella, B.; Marsaud, V.; Arpicco, S.; Geraud, G.; Cattel, L.; Couvreur, P.; Renoir, J. M. Journal of Drug Targeting 2007, 15(2), 146 https://doi.org/10.1080/10611860600935826

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