Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
권호 표지
DOI QR코드

DOI QR Code

Anthelmintic, antimicrobial and antipyretic activity of various extracts of Clerodendrum infortunatum Linn. leaves

  • Published : 2008.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

In the present study, various extracts of Clerodendrum infortunatum leaves have been studied for its anthelmintic, antimicrobial and antipyretic activities. In the anthelmintic and antipyretic study it was observed that the benzene extract was more potent than the other two extracts (ethanol and aqueous) even though all the three extracts were endowed with both the properties. The study reveals antimicrobial activity of the extracts against the tested strains of microorganisms between concentration ranges of $75\;{\mu}g/ml$ and $350\;{\mu}g/ml$ and shows effectiveness more against gram-positive bacteria than the gram-negative bacteria.

Keywords

References

  1. Anonymous. (1950) Wealth of India, Raw Materials, pp. 231-232, Vol. II, CSIR, New Delhi, India
  2. Bose A, Mondal S, Gupta JK, Ghosh T, Dash GK, Si S. (2007) Analgesic, anti-inflammatory and antipyretic activities of the ethanolic extract and its fractions of Cleome rutidosperma. Fitoterapia. (In Press) https://doi.org/10.1016/j.fitote.2007.05.002
  3. Chae S, Kim JS, Kang KA, Bu HD, Lee Y, Hyun JW, Kang SS. (2004) Antioxidant activity of Jionoside D from Clerodendron trichotomum. Biol. Pharm. Bull. 27, 1504-1508 https://doi.org/10.1248/bpb.27.1504
  4. Cruickshank R. (1968) Medical Microbiology: a guide to diagnosis and control of infection, pp. 888, $11^{th}$ ed., E and S Livingston Ltd, Edinburgh and London
  5. Ghosh T, Maity TK, Bose A, Dash GK. (2005) Anthelmintic activity of Bacopa monnieri. Indian J. Nat. Prod. 21, 16-19
  6. Ghosh T, Maity TK, Bose A, Dash GK, Das M. (2006) A study on antimicrobial activity of Bacopa monnieri Linn. aerial parts. J. Nat. Rem. 6, 170-173
  7. Harborne JB. (1984) Phytochemical Methods: A Guide to modern techniques of plant analysis, pp. 85-87, $2^{nd}$ ed., Chapman and Hall, New York
  8. Hazekamp A, Verpoorte R, Panthong A. (2001) Isolation of a bronchodilator flavonoid from the Thai medicinal plant Clerodendrum petasites. J. Ethnopharmacol. 78, 45-49 https://doi.org/10.1016/S0378-8741(01)00320-8
  9. Jigna P, Rathish N, Sumitra C. (2005) Preliminary screening of some folklore medicinal plants from Western India for potential antimicrobial activity. Indian J. Pharmacol. 37, 408-409
  10. Kirtikar KR, Basu BP. (1957) Indian Medicinal Plants, pp.1950, Vol. II, $3^{rd} edition, Bishen Singh Mahendrapal Singh, Dehradun, India
  11. Rastogi RP, Mahrotra BN. (2002) Compendium of Indian Medicinal Plants, pp. 679-683, Vol. III, CDRI, Luckhnow, India
  12. Subramanian SS, Nair AGR. (1973) Scutellarin and hispidulin-7-0-glucuronide from the leaves of Clerodendrum indicum and Clerodendron infortunatum. Phytochemistry 12, 1195 https://doi.org/10.1016/0031-9422(73)85054-X
  13. Thorn GW, Adams RD, Braunwald E, Isselbacher KJ, Petersdorf RG. (1977) Harrison's Principle of Internal Medicine, pp.1088, McGraw Hill Co., New York
  14. Trease GE, Evans WC. (1989) Pharmacognosy, pp. 171, $13^{th}$ ed, ELBS Publication, Delhi, India
  15. Vidyarthi RD. (1977) A Textbook of Zoology, pp. 329, $14^{th}$ ed, S. Chand and Co., New Delhi, India
  16. Vigar Z. (1984) Atlas of Medical Parasitology, pp.216, $2^{nd}$ed, P.G. Publishing House, Singapore
  17. Walker R, Edward C. (1999) Clinical Pharmacy and Therapeutics, pp.497, $2^{nd}$ ed, Churchill Livingston, London