Fisheries and Aquatic Sciences

The Korean Society of Fisheries and Aquatic Science (한국수산과학회)
권호 표지
DOI QR코드

DOI QR Code

Evolutionary History of Two Paralogous Glyceraldehyde 3-Phosphate Dehydrogenase Genes in Teleosts

  • Published : 2008.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Glyceraldehyde 3-phosphate dehydrogenase(GAPDH) is a key enzyme for carbohydrate metabolism in most living organisms. Recent reports and our own searches of teleost species in publicly available genomic databases have identified at least two distinct GAPDH genes in a given species. The two GAPDH genes are located on the same chromosome in teleosts, whereas they are located on the different chromosomes in mammals. Thus, we reconstructed a phylogenetic tree to better understand the evolutionary history of the GAPDH genes in the vertebrate lineage. Our phylogenetic analysis revealed unambiguously that the two GAPDH genes of teleosts are phylogenetically closely affiliated to one of the cytosolic GAPDH and spermatogenic GAPDH-S of mammals. This indicates that the two paralogous GAPDH genes shared a common ancestor and subsequently underwent a gene duplication event during early vertebrate evolution. However, GAPDH-S of teleosts showed significant differences in the polypeptide residues and tissue distribution of its mRNA transcripts from that of mammals, implying they have undergone a different history of functionalization.

Keywords

References

  1. Blomme, T., K. Vandepoele, S. De Bodt, C. Simillion, S. Maere and Y. Van de Peer. 2006. The gain and loss of genes during 600 million years of vertebrate evolution. Genome Biol., 7, R43 https://doi.org/10.1186/gb-2006-7-5-r43
  2. Chuang, D.M., C. Hough and V.V. Senatorov. 2005. Gly-ceraldehyde 3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu. Rev. Phar-macol. Toxicol., 45, 269-290 https://doi.org/10.1146/annurev.pharmtox.45.120403.095902
  3. Felsenstein, J. 1985. Confidence limits on phylogenies: an approach using the bootstrap. Evolution, 39, 783-791 https://doi.org/10.2307/2408678
  4. Figge, R.M., M. Schubert, H. Brinkmann and R. Cerff. 1999. Glyceraldehyde 3-phosphate dehydrogenase gene diversity in eubacteria and eukaryotes: evidence for intra- and inter-kingdom gene transfer. Mol. Biol. Evol., 16, 429-440 https://doi.org/10.1093/oxfordjournals.molbev.a026125
  5. Holland, J.P., L. Labieniec, C. Swimmer and M.J. Holland. 1983. Homologous nucleotide sequences at the 5' termini of messenger RNAs synthesized from the yeast enolase and glyceraldehyde-3-phosphate dehy-drogenase gene families: the primary structure of a third yeast glyceraldehydes 3-phosphate dehydro-genase gene. J. Biol. Chem., 258, 5291-5299
  6. Huang, X.-Y., L.A.M. Barrios, P. Vonkhorporn, S. Honda, D.G. Albertson and R.M. Hecht. 1989. Genomic organization of the glyceraldehydes 3-phosphate de-hydrogenase gene family of Caenorhabditis elegans. J. Mol. Biol., 206, 411-424 https://doi.org/10.1016/0022-2836(89)90490-7
  7. Liaud, M.-F., C. Lichtlé K. Apt, W. Martin and R. Cerff. 2000. Compartment-specific isoforms of TPI and GAPDH are imported into diatom mitochondria as a fusion protein: evidence in favor of a mitochondrial origin of the eukaryotic glycolytic pathway. Mol. Biol. Evol., 17, 213-223 https://doi.org/10.1093/oxfordjournals.molbev.a026301
  8. Manchado, M., C. Infante, E. Asensio and P. Canavate. 2007. Differential gene expression and dependence on thyroid hormones of two glyceraldehydes 3-phosphate dehydrogenases in the flatfish Senegalese sole (Solea senegalensis Kaup). Gene, 400, 1-8 https://doi.org/10.1016/j.gene.2007.05.008
  9. Martin, W., H. Brinkmann, C. Savonna and R. Cerff. 1993. Evidence for a chimeric nature of nuclear genomes: eubacterial origin of eukaryotic glyceraldehydes 3-phosphate dehydrogenase genes. Proc. Natl. Acad. Sci. USA, 90, 8692-8696
  10. Miki, K., W. Qu, E.H. Goulding, W.D. Willis, D.O. Bunch, L.F. Strader, S.D. Perreault, E.M. Eddy and D.A. O'Brien. 2004. Glyceraldehyde 3-phosphate dehydro-genase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proc. Natl. Acad. Sci. USA, 101, 16501-16506
  11. Petersen, J., H. Brinkmann and R. Cerff. 2003. Origin, evolution, and metabolic role of a novel glycolytic GAPDH enzyme recruited by land plant plastids. J. Mol. Evol., 57, 16-26 https://doi.org/10.1007/s00239-002-2441-y
  12. Sirover, M.A. 1999. New insights into an old protein: the functional diversity of mammalian glyceraldehydes 3-phosphate dehydrogenase. Biochim. Biophys. Acta, 1432, 159-184 https://doi.org/10.1016/S0167-4838(99)00119-3
  13. Sirover, M.A. 2005. New nuclear functions of the gly-colytic protein, glyceraldehydes 3-phosphate dehydro-genase, in mammalian cells. J. Cell. Biochem., 95, 45-52 https://doi.org/10.1002/jcb.20399
  14. Steinke, D., S. Hoegg, H. Brinkmann and A. Meyer. 2006. Three rounds (1R/2R/3R) of genome duplications and the evolution of the glycolytic pathway in vertebrates. BMC Biol., 4, 16 https://doi.org/10.1186/1741-7007-4-16
  15. Swofford, D.L. 2002. PAUP: Phylogenetic Analysis Using Parsimony (and Other Methods). Ver 4.0b10, Sinauer Associates Inc., Sunderland, MA, USA
  16. Tso, J.Y., X.H. Sun and R. Ray. 1985. Structure of two unlinked Drosophila melanogaster glyceraldehydes 3-phosphate dehydrogenase genes. J. Biol. Chem., 260, 8220-8228
  17. Welch, J.E., R.R. Barbee, P.L. Magyar, D.O. Bunch and D.A. O'Brien. 2006. Expression of the spermatogenic cell-specific glyceraldehyde 3-phosphate dehydro-genase (GAPDS) in rat testis. Mol. Reprod. Dev., 73, 1052-1060 https://doi.org/10.1002/mrd.20235
  18. Xia, X. and Z. Xie. 2001. DAMBE: Data analysis in molecular biology and evolution. J. Hered., 92, 371-373 https://doi.org/10.1093/jhered/92.4.371

Cited by

  1. Validity of Photo-identification Method for Spotted Seals on Baekryongdo, Korea vol.43, pp.4, 2010, https://doi.org/10.5657/kfas.2010.43.4.340
  2. Genomic Organization, Tissue Distribution and Developmental Expression of Glyceraldehyde 3-Phosphate Dehydrogenase Isoforms in Mud Loach Misgurnus mizolepis vol.16, pp.4, 2013, https://doi.org/10.5657/FAS.2013.0291
  3. ) vol.14, pp.4, 2014, https://doi.org/10.1111/1755-0998.12223
  4. 제주 연안에 출현하는 큰돌고래(Bottlenose dolphins) 연안 정착성 개체군 vol.42, pp.6, 2008, https://doi.org/10.5657/kfas.2009.42.6.650
  5. Isoform-specific response of two GAPDH paralogs during bacterial challenge and metal exposure in mud loach (Misgurnus mizolepis: Cypriniformes) kidney and spleen vol.24, pp.3, 2011, https://doi.org/10.7847/jfp.2011.24.3.269