한국수정란이식학회지 (Journal of Embryo Transfer)

  • 제23권3호
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  • Pages.177-181
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  • 2008
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  • 2508-755X(pISSN)
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  • 2288-0178(eISSN)
한국수정란이식학회 (The Korean Society of Embryo Transfer)
권호 표지

hCG 투여가 복제란 이식 한우 대리모의 임신과 Progesterone 농도에 미치는 영향

Effects of hCG Treatment on the Pregnancy Rates and Progesterone Concentrations in Hanwoo Recipients with SCNT Embryos

  • 황성수 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 양병철 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 임기순 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 고응규 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 최선호 (농촌진흥청 축산과학원 축산기술지원과) ;
  • 민관식 (한경대학교 생물환경.정보통신전문대학원) ;
  • 윤종택 (한경대학교 생물환경.정보통신전문대학원) ;
  • 성환후 (농촌진흥청 축산과학원 응용생명공학과)
  • Hwang, Seong-Soo (Animal Biotechnology Division, National Institute of Animal Science, RDA) ;
  • Yang, Byoung-Chul (Animal Biotechnology Division, National Institute of Animal Science, RDA) ;
  • Im, Gi-Sun (Animal Biotechnology Division, National Institute of Animal Science, RDA) ;
  • Ko, Yeoung-Gyu (Animal Biotechnology Division, National Institute of Animal Science, RDA) ;
  • Choi, Sun-Ho (Technology Application Division, National Institute of Animal Science, RDA) ;
  • Min, Kwan-Sik (Graduate School of Bio-& Information Technology, Hankyong University) ;
  • Yoon, Jong-Taek (Graduate School of Bio-& Information Technology, Hankyong University) ;
  • Seong, Hwan-Hoo (Animal Biotechnology Division, National Institute of Animal Science, RDA)
  • 발행 : 2008.09.30
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초록

This study was performed to investigate the effects of hCG treatment on pregnancy and delivery rates in the Hanwoo recipients. There were significantly higher pregnancy and delivery rates in the recipients treated with hCG at 7 days after artificial insemination (p<0.05), respectively. The SCNT embryos from bovine fetal fibroblast cells were transferred into the synchronized recipients. The recipients were administered saline (n=89) or hCG (1,500 IU) (n=48) at 7 days after heat, respectively. The pregnancy rate was significantly higher in the recipients treated with hCG compared to that of saline treated group (p<0.01), however, the delivery rate was not different in both treated groups. The concentration of plasma progesterone (P4) was not different in both groups before hCG treatment, but the P4 level was increased significantly in hCG treated group after hCG injection (p<0.05). Although the pregnancy rate was very high in early stage of pregnancy, it was decreased dramatically after 50 days of pregnancy and maintained basal level. Taken together, the treatment of hCG in the SCNT recipients after day 7 of heat was effective method to increase the P4 concentration and to increase the pregnancy rate. But it did not affect directly to delivery.

키워드

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