Journal of the Korean Ceramic Society (한국세라믹학회지)

The Korean Ceramic Society (한국세라믹학회)
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Effect of Collagen Treatment on Bioactivity of Ti-6Al- 7Nb and Ti-6Al-4V Alloys

Ti-6Al-7Nb and Ti-6Al-4V 합금의 생체활성에 미치는 콜라겐 처리의 영향

  • Kim, Tae-Ho (Department of Advanced Materials Engineering, Chungnam National University) ;
  • Lee, Kap-Ho (Department of Advanced Materials Engineering, Chungnam National University) ;
  • Hong, Sun-Ig (Department of Advanced Materials Engineering, Chungnam National University)
  • 김태호 (충남대학교 신소재공학과) ;
  • 이갑호 (충남대학교 신소재공학과) ;
  • 홍순익 (충남대학교 신소재공학과)
  • Published : 2008.10.31
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Abstract

Biomimetic apatite formation and deposition behaviors of Ti-6Al-7Nb and Ti-6Al-4V plates in simulated body fluids(SBF) under various conditions were examined. In case of regular samples without collagen treatments the weight gain due to apatite precipitation on the surface in Ti-6Al-4V was found to be higher than in Ti-6Al-7Nb. In case of collagen-coated samples, the weight gain in Ti-6Al-4V continued to be higher than in Ti-6Al-7Nb, but the difference between the two became smaller. Both Ti-6Al-7Nb and Ti-6Al-4V samples with collagen coating exhibited an appreciable increase of weight gain, which may be caused by the interaction between collagen and $Ca^{+2}$ ions. The weight gain was found to be not much affected by the addition of collagen to SBF. The ill-defined granular structure in the presence of collagen can be associated with the increasing volume fraction of amorphous calcium phosphate.

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References

  1. L. Jonasova, F. A. Muller, A. Helebrant, J. Strnad, and P. Greil, "Biomimetic Apatite Formation on Chemically Treated Titanium," Biomaterials, 25 1187-94 (2004) https://doi.org/10.1016/j.biomaterials.2003.08.009
  2. T. J. Webster and J. U. Ejiofer, "Increased Osteoblast Adhesion on Nanophase Metals: Ti, Ti6Al4V, and CoCrMo.," Biomaterials, 25 4731-39 (2004) https://doi.org/10.1016/j.biomaterials.2003.12.002
  3. R. Godley, D. Starosvetsky, and I. Gotman, "Bonelike Apatite Formation on Niobium Metal Treated in Aqueous NaOH.," J. Mater. Sci.: Materials in Medicine, 15 1073-81 (2004) https://doi.org/10.1023/B:JMSM.0000046388.07961.81
  4. Kokubo T. "Biocative Glass Ceramics: Properties and Application," Biomaterials, 12 155-63 (1991) https://doi.org/10.1016/0142-9612(91)90194-F
  5. Hench LL., "Bioceramics: from Concept to Clinic," J. Am. Ceram. Soc., 74 1487-510 (1991) https://doi.org/10.1111/j.1151-2916.1991.tb07132.x
  6. Jonasova L, Helebrant A, and Sanda L., "The Influence of Simulated Body Fluid Composition on Carbonated Hydroxyapatite Formation," Ceram-Silikaty, 46 9-14 (2002)
  7. Scharnweber D, Born R, Flade K, Roessler S, Stoelzel M, and Worch H, "Mineralization Behaviour of Collagen Type I Immobilized on Different Substrates," Biomaterials, 25 2371-80 (2004) https://doi.org/10.1016/j.biomaterials.2003.09.025
  8. Li P, Ohtsuki Ch, Kokubo T, Nakanishi K, Soga N, and de Groot K, "The Role of Hydrated Silica, Titania, and Alumina in Inducing Apatite on Implants," J. Biomed Mater. Res., 28 7-15 (1994) https://doi.org/10.1002/jbm.820280103
  9. Li P, Kangasniemi I, de Groot K, and Kokubo T, "Bonelike Hydroxyapatite Indiction by a Gel-derived Titania on a Titanium Substrate," J. Am. Ceram. Soc., 5 1307-12 (1994)
  10. Anna T, Giancarlo C, Elena L, Monica S, Norberto R, and Giuseppe F, "Biologically Inspired Collagen Fibers/hydoxyapatite Nanocrystals," J. Biomed Mater. Res., 67A:618 (2002)
  11. Roveria N, Falinia G, Sidotia MC, Tampierib A, Landib E, Sandrib M, et al., "Biologically Inspired Growth of Hydroxyapatite Nanocrystals Inside Self-assembled Collagen Fibers," Mater. Sci. Eng. C, 23 441-47 (2003) https://doi.org/10.1016/S0928-4931(02)00318-1
  12. Kikuchi M, Itoh S, Ichinose S, Shinomiya K, and Tanaka J, "Self-organization Mechanism in a Bone-like Hydroxyapatite/ collagen Nanocomposite Synthesized in Vitro and its Biological Reaction in Vivo," Biomaterials, 22 1705-11 (2001) https://doi.org/10.1016/S0142-9612(00)00305-7
  13. Zhang LJ, Feng XS, Liu HG, Qian DJ, Zhang L, Yu XL, et al., "Hydroxyapatite/collagen Composite Materials Formation in Simulated Body Fluid Environment," Mater. Lett., 58 719-24 (2004) https://doi.org/10.1016/j.matlet.2003.07.009
  14. J. Kim, Y. C. Choi, H. S. Kim, and S. I. Hong, "Biomimetic Deposition of Apatite on Zr-1Nb and Ti-6Al-4V," Materials Science Forum, 1013 534-36 (2007)
  15. S. I. Hong, K. H. Lee, M. E. Outslay, and D. H. Kohn, "Ultrastructural Analyses of Nanoscale Apatite Biomimetically Grown on Organic Template," J. Mater. Res, 23 478-85 (2008) https://doi.org/10.1557/jmr.2008.0051
  16. M. Aizawa, A. E. Porter, S. M. Best, and W. Bonfield, "Ultrastrural Observation of Single-crystal Apatite Fibres," Biomaterials, 25 4327-33 (2005)
  17. L. Luong, S. I. Hong, R. J. Patel, M. Outslay, and D. H. Kohn, "Spatial Control of Protein within Biomimetically Nucleated Mineral," Biomaterials, 27 1175-86 (2006) https://doi.org/10.1016/j.biomaterials.2005.07.043
  18. E.D. Eanes: "Dynamics of Calcium Phosphate Precipitation, in Calcification in Biological Systems," p. 1, edited by E. Bonucci, CRC Press, Boca Raton, FL, 1992
  19. J. H. Kim, Y. C. Choi, H. S. Kim, and S. I. Hong, "Biocompatibility and Mechanical Performance of Ni-Ti," Materials Science Forum, 1017 534-36 (2007)
  20. S. Rammelt, E. Schulze, R. Berhardt, U. Hanisch, D. Scharnweber, H. Worch, H. Zwipp, and A. Biewener, "Coating of Titanium Implants with Type-i Collagen," J. Orthopaedic Research, 22 1025-34 (2004) https://doi.org/10.1016/j.orthres.2004.02.011