대한한방소아과학회지 (The Journal of Pediatrics of Korean Medicine)
- 제21권2호
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- Pages.89-96
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- 2007
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- 1226-8038(pISSN)
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- 2287-9463(eISSN)
사청환(瀉靑丸)이 thiaocetamide에 의한 백서(白鼠) 간손상(肝損傷)에 미치는 영향
Effects of Sachunghwan Extract on Liver Damage in Thioacetamide Induced Rats
- 채중원 (동신대학교 한의과대학 소아과학교실)
- Chai, Jung-Won (Department of Pediatrics, College of Oriental Medicine. Dong-shin University)
- 발행 : 2007.08.31
초록
Objectives The purpose of this study is to examine of the effect of Sachunghwan on the liver disease. Methods It was induced liver damage rats by thioacetamide and dosed the extract orally and measured the activity rate of GOT, GPT, ALP and LDH. Results 1. GOT activity was more decreased in the experimental goup than in the control goup. Group I showed continuous significance after 72 hour, Group II was significance after 96 hours. 2. GPT activity was more decreased in the experimental group than in the control group. Group I was effective after 72 hours, but group II was effective after 96 hours. 3. The significance of ALP activity in the Group I and group II was revealed after 72 hours. 4. The significance of LDH activity in the Group I and group II was revealed after 96 hours. Conclusions It was showded that Sachunghwan extract was effective on liver disease.