Korean Journal of Acupuncture
- Volume 24 Issue 2
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- Pages.163-184
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- 2007
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- 2287-3368(pISSN)
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- 2287-3376(eISSN)
A Study on the Effect of Herbal-acupuncture with Phellodendri Cortex Solution on Collagen-induced Arthritis in DBA/1J Mice
황백약침이 콜라겐 유도 관절염 생쥐에 미치는 영향
- Kim, Jae-Young (Dept. of Acupuncture & Moxibustion College of Oriental Medicine, Daejeon University) ;
- Lee, Hyun (Dept. of Acupuncture & Moxibustion College of Oriental Medicine, Daejeon University)
- Published : 2007.06.30
Abstract
Objectives & Methods : The purpose of this study is to observe the effects of Phellodendri Cortex Herbal-acupuncture solution (PC-HAS) at Joksamni (ST36) on collagen II induced arthritis in DBA-1J mice. The author performed several experimental items to analyze arthritis evaluation, change of weight, spleen size and adhesion rate, change of cytokine level, IgG, IgM and anti-collagen II, chang of immunocyte count, histological change of CIA mouse joint. Results : 1. In the PC-HA group, arthritis index, the incidence of arthritis and joint edema were significantly decreased. 2. In the PC-HA group, the change of spleen size, spleen adhesion rate and the knee joint were significantly decreased. 3. The levels of
Keywords
- Phellodendri Cortex;
- Rheumatoid Arthritis (RA);
- ST36;
- Herbal-Acupuncture;
- Collagen-induced Arthritis (CIA)