A study on the anti-oxidative effect of electroacupuncture at Wijung (BL40) in rats

위중전침의 항산화 효과에 대한 실험적 연구

  • Kim, Kwang-Sung (Dept. of Meridian &Acupoint, College of Oriental Medicine, Daejeon University) ;
  • Hong, Kwon-Eui (Dept. of Acupuncture & Moxibustion College of Oriental Medicine, Daejeon University) ;
  • Yim, Yun-Kyoung (Dept. of Meridian &Acupoint, College of Oriental Medicine, Daejeon University)
  • 김광성 (대전대학교 한의과대학 경락경혈학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실) ;
  • 임윤경 (대전대학교 한의과대학 경락경혈학교실)
  • Published : 2007.03.27

Abstract

Objectives : The purpose of this study is to observe the anti-oxidative effects of electroacupuncture at Wijung (BL40) in rats. Methods : The author performed several experimental items including measurements of body weight, liver index, levels of albumin, total bilirubin, LDL-cholesterol, LDH, GOT and GPT in blood serum, and levels of SOD, glutathione, catalase, No and MDA (malondialdehyde) in liver, histological analysis of liver. Results : 1. In the BL40-EA group, liver index was decreased significantly compared to those of the control group, the holder group and the sham-EA group. 2. In the BL40-EA group, the albumin level was increased significantly compared to those of the control and holder group. LDL-cholesterol and GOT level were increased significantly compared to those of the control group and the holder group. 3. In the BL40-EA group, the SOD activity & the Catalase activity were decreased significantly compared to those of the control group and the holder group. 4. In the BL40-EA group, the density of liver tissue was more similarly maintained to the normal group compared to those of the control group and the holder group. Conclusion : These results suggest that electroacupuncture at BL40 has an antioxidant effect in human, and hereafter continuous study & clinical application is needed.

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